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Table 3 Haplotype analysis of IL12B.

From: Analysis of eight genes modulating interferon gamma and human genetic susceptibility to tuberculosis: a case-control association study

Block 1a

Frequency Cases

Frequency Controls

p value

1

A-G-T-S-G-G

0.63

0.62

0.61

2

C-G-C-L-T-C

0.25

0.24

0.49

3

A-A-T-S-G-G

0.06

0.09

0.02

4

C-G-C-L-T-G

0.03

0.04

0.38

Global significance b

 

0.11

  1. a The order of the SNPs in each block corresponds to Figure 1, with D5S2941 included and rs3213096 excluded due to its low allele frequency in the SAC population.
  2. b Global significance were calculated in COCAPHASE [38] and 10 000 permutations were done.