From: The first wave of pandemic influenza (H1N1) 2009 in Germany: From initiation to acceleration
Number of cases with information | Initiation period (%)a | Acceleration period (%)a | |
---|---|---|---|
Total | 53,968 | 23,789 (44.1) | 30,179 (55.9) |
Age groups | 53,930 | 23,783 | 30,147 |
Median [quartiles] | 19 [16,26]# | 15 [10,26]# | |
0-4 years | 2,076 | 516 (2.2) | 1,560 (5.2) |
5-14 years | 16,989 | 3,794 (16.0) | 13,195 (43.8) |
15-24 years | 20,295 | 12,854 (54.0) | 7,441 (24.7) |
25-59 years | 13,975 | 6,398 (26.9) | 7,577 (25.1) |
≥ 60 years | 595 | 221 (0.9) | 374 (1.2) |
Origin of infection | 53,757 | 23,714 | 30,043 |
Autochthonous cases | 37,573 | 9,235 (38.9) | 28,338 (94.3) |
Risk factors | 39,748 | 17,579 | 22,169 |
All cases | 820 (4.7)* | 1,539 (6.9)* | |
Autochthonous cases | 27,486 | 411/6,868 (6.0)** | 1,458/20,618 (7.1)** |
Imported cases | 12,140 | 405/10,644 (3.8)** | 77/1,476 (5.2)** |
Risk factors | |||
Chronic diseases | |||
Respiratory disease | 1,080 | 372 (2.1) | 708 (3.2) |
Cardio-vascular disease | 264 | 107 (0.6) | 157 (0.7) |
Diabetes | 173 | 63 (0.4) | 110 (0.5) |
Obesity§ | 159 | 71 (0.4) | 88 (0.4) |
Immunosuppression | 112 | 40 (0.2) | 72 (0.3) |
Other chronic diseases | 458 | 127 (0.7) | 331 (1.5) |
Pregnancy | 113 | 40 (0.2) | 73 (0.3) |
Age groups | 39,748 | 17,533 | 22,043 |
0-4 years | 1,474 | 17/367 (4.6) | 53/1.107 (4.8) |
5-14 years | 12,351 | 101/2,831 (3.6) | 571/9,520 (6.0) |
15-24 years | 15,107 | 314/9,510 (3.3) | 291/5,597 (5.2) |
25-59 years | 10,368 | 350/4,711 (7.4) | 560/5,657 (9.9) |
≥ 60 years | 429 | 38/157 (24.2) | 63/272 (23.2) |
Symptoms | 53,968 | 23,789 | 30,179 |
ILI | 2,318 (9.7) | 2,924 (9.7) | |
Diagnosis | |||
Time interval between onset of symptoms and diagnosis | 7.253 | 3 days [2, 5]# | 2 days [1,4]# |
Antiviral treatment initiated | 35,160 | 15,941 | 19,219 |
All cases | 4,671 (29.3) | 4.491 (24.7) | |
Cases with underlying chronic disease | 2,092 | 319/743 (42.9) | 598/1,278 (46.8) |
Cases without risk factors | 33,139 | 4,352/15,198 (28.6) | 3,893/17,941 (21.7) |
Pregnancy | 88 | 6/34 (17.6) | 13/54 (24.1) |
Time interval between symptom onset and start of therapy | 2 days [1,3]# | 1 day [1,2]# | |
Pneumonia | 40,729 | 18,090 | 22,639 |
All cases with pneumonia | 275 | 93 (0.5) | 182 (0.8) |
Antiviral treatment initiated | 219 | 33/77 (42.9) | 56/142 (39.4) |
Cases with underlying chronic disease | 76 | 19/764 (2.5) | 57/1,410 (4.0) |
Cases without risk factors | 176 | 66/16,303 (0.4) | 110/20,192 (0.5) |
Pregnancy | 99 | 1/37 (2.7) | 1/62(1.6) |
Hospitalisation | 52,485 | 23,665 | 28,820 |
All cases hospitalised | 2,084 | 1,117 (4.7)* | 967 (3.4)* |
Age (years) | 19 [16,26]# | 15 [11,26]# | |
Cases with risk factors | 2,342 | 102/814 (12.5) | 182/1,528 (11.9) |
Age (years) | 23 [16,41] # | 17 [11, 39] # | |
Cases without risk factors | 37,187 | 618/16,711 (3.7)* | 597/20.476 (2.9)* |
Age (years) | 19 [16,25]# | 15 [10,25]# |