Variable | HIV-negative n/N (%) | HIV-positive n/N (%) | P | Risk ratio# (95%CI) | ||
---|---|---|---|---|---|---|
Prevalence of high-risk HPV | Â | Â | Â | Â | Â | Â |
Any high-risk HPV infection* | N = 503 | 229 (45.5) | N = 273 | 200 (73.3) | <0.001 | 1.7 (1.5-1.9) |
   Type 16 |  | 56 (11.1) |  | 66 (24.2) | <0.001 | 2.4 (1.7-3.4) |
   Type 18 |  | 34 (6.8) |  | 51 (18.7) | <0.001 | 2.9 (1.9-4.6) |
   Type 31 |  | 31 (6.2) |  | 33 (12.1) | 0.004 | 2.0 (1.2-3.4) |
   Type 33 |  | 1 (0.2) |  | 3 (1.1) | 0.095 | 4.3 (0.41-45.8) |
   Type 35 |  | 39 (7.8) |  | 49 (18.0) | <0.001 | 2.7 (1.7-4.1) |
   Type 39 |  | 20 (4.0) |  | 36 (13.2) | <0.001 | 4.2 (2.3-7.5) |
   Type 45 |  | 18 (3.6) |  | 21 (7.7) | 0.012 | 2.3 (1.3-4.2) |
   Type 51 |  | 32 (6.4) |  | 39 (14.3) | <0.001 | 2.5 (1.5-4.1) |
   Type 52 |  | 38 (7.6) |  | 70 (25.6) | <0.001 | 3.7 (2.5-5.6) |
   Type 53 |  | 35 (7.0) |  | 56 (20.5) | <0.001 | 3.0 (2.0-4.6) |
   Type 56 |  | 24 (4.8) |  | 39 (14.3) | <0.001 | 2.9 (1.7-4.9) |
   Type 58 |  | 21 (4.2) |  | 15 (5.5) | 0.40 | 1.4 (0.7-2.7) |
   Type 59 |  | 43 (8.6) |  | 36 (13.2) | 0.04 | 1.7 (1.1-2.6) |
   Type 66 |  | 37 (7.4) |  | 40 (14.7) | 0.001 | 2.1 (1.3-3.3) |
   Type 68 |  | 2 (0.4) |  | 6 (2.2) | 0.02 | 5.5 (1.0-29.0) |
Mean high-risk HPV types (sd) | Â | 0.8 (1.1) | Â | 1.8 (1.8) | <0.001 | Â |
Low risk HPV | Â | Â | Â | Â | Â | Â |
   Type 6 | N = 503 | 13 (2.6) | N = 273 | 10 (3.7) | 0.40 | 1.4 (0.63-3.3) |
   Type 67 |  | 87 (17.3) |  | 84 (30.8) | <0.001 | 1.8 (1.4-2.4) |
Viral load of high-risk HPV types (n≥1 copy/cell; median (IQR)) |  |  |  |  |  |  |
   Type 16 |  | 38; 32.5 (4-472) |  | 52; 145 (12-3278) | 0.016 |  |
   Type 18 |  | 18; 12 (4-58) |  | 31; 31 (6-718) | 0.23 |  |
   Type 31 |  | 22; 15 (3-572) |  | 25; 208 (58-13 257) | 0.02 |  |
   Type 33 |  | 1; 204 (NA) |  | 3; 15 453 (251-45 601) | 0.18 |  |
   Type 35 |  | 34; 118 (14-4882) |  | 48; 302 (61-9969) | 0.11 |  |
   Type 39 |  | 14; 13 (1-89) |  | 25; 106 (3-2600) | 0.06 |  |
   Type 45 |  | 14; 8 (2-24) |  | 21; 49 (4-252) | 0.04 |  |
   Type 51 |  | 30; 43 (3-1738) |  | 37; 826 (34-43 983) | 0.02 |  |
   Type 52 |  | 31; 12 (3-71) |  | 59; 76 (5-938) | 0.05 |  |
   Type 53 |  | 27; 5 (2-14) |  | 47; 31 (1-288) | 0.14 |  |
   Type 56 |  | 20; 112 (5.5-829) |  | 31; 219 (20-1511) | 0.39 |  |
   Type 58 |  | 12; 16 (4.5-67) |  | 13; 7 (4-32) | 0.81 |  |
   Type 59 |  | 21; 27 (3-235) |  | 20; 437 (20-3552) | 0.04 |  |
   Type 66 |  | 22; 4 (2-794) |  | 35; 48 (7-1193) | 0.07 |  |
   Type 68 |  | 0; 0 |  | 1; 1; (NA) | - |  |
Total high-risk HPV viral load | Â | 48 (6-756) | Â | 811 (33-12 110) | <0.001 | Â |
Cervical cytology (Pap smear) | Â | Â | Â | Â | Â | Â |
   Normal | N = 503 | 461 (91.7) | N = 269 | 196 (72.9) |  |  |
   ASC-US/ASC-H |  | 8 (1.6) |  | 6 (2.2) |  |  |
   LSIL |  | 21 (4.2) |  | 54 (20.1) |  |  |
   HSIL |  | 12 (2.4) |  | 13 (4.8) |  |  |
   Invasive carcinoma |  | 1 (0.2) |  | 0 (0) | <0.001 |  |