High rate of pneumococcal bacteremia in a prospective cohort of older children and adults in an area of high HIV prevalence in rural western Kenya

Table 4 Rates of pneumococcal bacteremia in rural western Kenya, October 2006 - September 2008

Age in years	*Syndrome*	*S. pneumo*(n)	Pyo^a	Rate per 100,000 Pyo (95% CI)	% cultured	Rate, Extrapolation 1^bPyo (95% CI)	% clinic visits to Lwak	Rate Extrapolation 2^cPyo (95% CI)
5.17	Overall	11	17917	61 (31-110)	--	160 (65-255)		301 (123-479)
	SARI Inpatient	5			64		95
	SARI Outpatient	4			47		54
	Admit, not SARI	0			45		95
	Fever, not SARI	2			38		41
18-34	Overall	22	10869	202 (127-306)	--	391 (227-554)		578 (336-820)
	SARI Inpatient	10			56		80
	SARI Outpatient	8			60		51
	Admit, not SARI	4			36		79
	Fever, not SARI	0			40		43
35-49	Overall	10	4939	202 (97-372)	--	407 (155-659)		591 (225-957)
	SARI Inpatient	5			66		77
	SARI Outpatient	2			55		52
	Admit, not SARI	3			34		72
	Fever, not SARI	0			62		42
≥50	Overall	9	6738	134 (61-253)		232 (80-384)		354 (123-585)
	SARI Inpatient	7			71		67
	SARI Outpatient	0			46		45
	Admit, not SARI	2			35		63
	Fever, not SARI	0			44		38
Overall		52	40463	129 (96-169)		245 (178-312)		419 (305-533)

^apyo - person years of observation
^bExtrapolation 1 accounts for patients meeting case definitions for blood culture in Lwak clinic who did not have blood cultures done (see methods).
^cExtrapolation 2 uses the rates for extrapolation 1 and extrapolates further by accounting for the % of persons at the biweekly home visit with SARI or fever who went to a clinic other than Lwak clinic (see methods).

ISSN: 1471-2334