Cross-sectional study of availability and pharmaceutical quality of antibiotics requested with or without prescription (Over The Counter) in Surabaya, Indonesia

Table 3 Antibiotic content of 104 oral samples purchased in medicine outlets in Surabaya, Indonesia

Antibiotic	Required active substance (%, min, max)	Number of samples		Content of active substance mg (% of stated dosage)/tablet or capsule		Content too low^a
		Pharmacy	Kiosk/Drug store	Min	Max	N (%)
Amoxicillin 500 mg tablet	92.5 - 110	9	11	457 (91.4)	481 (96.2)	4 (25)^b
Chloramphenicol 250 mg capsule	95 - 105	19	4	239 (95.6)	260 (104)	0
Ciprofloxacin 500 mg tablet	95 - 105	17	2	481 (96.2)	506 (101.2)	0
Cotrimoxazole 400/80 mg tablet sulfamethoxazole trimethoprim	92.5 - 107.5 92.5 - 107.5	20	0	391 (97.8) 58 (72.5)	411 (102.8) 81 (101.3)	0 10 (50)^c
Tetracycline 250 mg capsule	95 - 105	8	10	226 (90.4)	259 (103.6)	5 (23)^d
Tetracycline 500 mg capsule	95 - 105	2	1	503 (100.6)	514 (102.8)	0

^aCompared with pharmacopeial limits [23]
^bTwo were obtained from a pharmacy; ^cAll were obtained from a pharmacy; ^dOne was obtained from a pharmacy

ISSN: 1471-2334