Skip to main content
Figure 2 | BMC Infectious Diseases

Figure 2

From: Prevalent HBV point mutations and mutation combinations at BCP/preC region and their association with liver disease progression

Figure 2

Combination patterns of viral mutations in patients with different diagnoses. Point utations identified in the PCR and clone sequencing were demonstrated along the x-axis. "0" represents strains without mutations in indicated sites. Only certain combinations were detected among a number of calculated possibilities. Grey parts illustrated combinations of no less than 3 sites, and their frequencies were on the right top. Mutation profiles were more complicated in patients of liver failure (LF), liver cirrhosis (LC) and hepatocellular carcinoma (HCC) than those of asymptomatic carrier (ASC) and chronic hepatitis (CH). Mutation combinations in LC and HCC patients were identified by both direct PCR sequencing and clone sequencing.

Back to article page