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Table 1 Baseline characteristics - comparing individuals who did not fully comply and individuals who were analysed and individuals in the treatment and placebo groups

From: Impact of repeated four-monthly anthelmintic treatment on Plasmodiuminfection in preschool children: a double-blind placebo-controlled randomized trial

  Individuals who did not comply
(N = 908)
Analysed individuals
(N = 320)
P-value Treatment Group
(N = 158)
Placebo Group
(N = 162)
P-value
Characteristic       
Age (years)       
   1 314 (34.6%) 108 (33.8%) 0.137a 59 (37.3%) 49 (30.2%) 0.085a
   2 202 (22.2%) 86 (26.9%)   38 (24.1%) 48 (29.6%)  
   3 204 (22.5%) 76 (23.8%)   31 (19.6%) 45 (27.8%)  
   4 188 (20.7%) 50 (15.6%)   30 (19%) 20 (12.3%)  
Sex       
   Male 475 (52.3%) 159 (49.7) 0.419a 85 (53.8%) 74 (45.7%) 0.146a
   Female 433 (47.7%) 161 (50.3)   73 (46.2%) 88 (54.3%)  
Village       
   Akinlalu 112 (12.3%) 73 (22.8%) < 0.001a 33 (20.9%) 40 (24.7%) 0.708a
   Ipetumodu 407 (44.8%) 128 (40%)   65 (41.1%) 63 (38.9%)  
   Moro 170 (18.7%) 49 (15.3%)   27 (17.1%) 22 (13.6%)  
   Edun-abon 219 (24.1%) 70 (21.9%)   33 (20.9%) 37 (22.8%)  
Socio-economic status index       
   Mean ± SE 6.52 ± 0.11 6.29 ± 0.06 0.058b 6.49 ± 0.15 6.56 ± 0.16 0.757b
Parasitic infections       
Plasmodium spp.f - -   71 (44.9%) 54 (33.3%) 0.033a
   Mean parasitaemiaf - -   2319 ± 511 1471 ± 341 0.025b
Ascaris lumbricoides 439 (48.3%) 146 (45.6%) 0.402a 73 (46.2%) 73 (45.1%) 0.838a
   Mean epg ± SE 1080 ± 167 1075 ± 88 0.500e 1146 ± 283 1016 ± 183 0.926b
Trichuris trichiura b 36 (4%) 10 (3.1%) 0.496a 4 (2.5%) 6 (3.7%) 0.750d
Hookwormb 40 (4.4%) 13 (4.1%) 0.795a 4 (2.5%) 9 (5.6%) 0.171a
Schistosoma haematobium b 11 (1.2%) 3 (0.9%) 1a 0 (0%) 3 (1.9%) 0.248d
Clinical indicator       
Malaria attacksf - -   4 (2.5%) 4 (2.5%) 1d
Haemoglobin (g/dl; mean ± S.E.) 9.75 ± 0.05 9.69 ± 0.09 0.542b 9.54 ± 0.12 9.88 ± 0.11 0.039b
Weight (kg; mean ± S.E.) 11.98 ± 0.09 11.56 ± 0.14 0.019b 11.48 ± 0.20 11.64 ± 0.21 0.576b
Height (cm; mean ± S.E.) 88.01 ± 0.35 86.61 ± 0.51 0.064e 85.64 ± 0.87 87.02 ± 0.72 0.221b
  1. a χ2 test
  2. b t-test
  3. c Mean epg not given as the number of eggs detected was very low
  4. d Fisher's exact test
  5. e Mann Whitney U
  6. f Data on malaria was only available for those individuals who were analysed