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Table 1 Baseline characteristics - comparing individuals who did not fully comply and individuals who were analysed and individuals in the treatment and placebo groups

From: Impact of repeated four-monthly anthelmintic treatment on Plasmodiuminfection in preschool children: a double-blind placebo-controlled randomized trial

 

Individuals who did not comply

(N = 908)

Analysed individuals

(N = 320)

P-value

Treatment Group

(N = 158)

Placebo Group

(N = 162)

P-value

Characteristic

      

Age (years)

      

   1

314 (34.6%)

108 (33.8%)

0.137a

59 (37.3%)

49 (30.2%)

0.085a

   2

202 (22.2%)

86 (26.9%)

 

38 (24.1%)

48 (29.6%)

 

   3

204 (22.5%)

76 (23.8%)

 

31 (19.6%)

45 (27.8%)

 

   4

188 (20.7%)

50 (15.6%)

 

30 (19%)

20 (12.3%)

 

Sex

      

   Male

475 (52.3%)

159 (49.7)

0.419a

85 (53.8%)

74 (45.7%)

0.146a

   Female

433 (47.7%)

161 (50.3)

 

73 (46.2%)

88 (54.3%)

 

Village

      

   Akinlalu

112 (12.3%)

73 (22.8%)

< 0.001a

33 (20.9%)

40 (24.7%)

0.708a

   Ipetumodu

407 (44.8%)

128 (40%)

 

65 (41.1%)

63 (38.9%)

 

   Moro

170 (18.7%)

49 (15.3%)

 

27 (17.1%)

22 (13.6%)

 

   Edun-abon

219 (24.1%)

70 (21.9%)

 

33 (20.9%)

37 (22.8%)

 

Socio-economic status index

      

   Mean ± SE

6.52 ± 0.11

6.29 ± 0.06

0.058b

6.49 ± 0.15

6.56 ± 0.16

0.757b

Parasitic infections

      

Plasmodium spp.f

-

-

 

71 (44.9%)

54 (33.3%)

0.033a

   Mean parasitaemiaf

-

-

 

2319 ± 511

1471 ± 341

0.025b

Ascaris lumbricoides

439 (48.3%)

146 (45.6%)

0.402a

73 (46.2%)

73 (45.1%)

0.838a

   Mean epg ± SE

1080 ± 167

1075 ± 88

0.500e

1146 ± 283

1016 ± 183

0.926b

Trichuris trichiura b

36 (4%)

10 (3.1%)

0.496a

4 (2.5%)

6 (3.7%)

0.750d

Hookwormb

40 (4.4%)

13 (4.1%)

0.795a

4 (2.5%)

9 (5.6%)

0.171a

Schistosoma haematobium b

11 (1.2%)

3 (0.9%)

1a

0 (0%)

3 (1.9%)

0.248d

Clinical indicator

      

Malaria attacksf

-

-

 

4 (2.5%)

4 (2.5%)

1d

Haemoglobin (g/dl; mean ± S.E.)

9.75 ± 0.05

9.69 ± 0.09

0.542b

9.54 ± 0.12

9.88 ± 0.11

0.039b

Weight (kg; mean ± S.E.)

11.98 ± 0.09

11.56 ± 0.14

0.019b

11.48 ± 0.20

11.64 ± 0.21

0.576b

Height (cm; mean ± S.E.)

88.01 ± 0.35

86.61 ± 0.51

0.064e

85.64 ± 0.87

87.02 ± 0.72

0.221b

  1. a χ2 test
  2. b t-test
  3. c Mean epg not given as the number of eggs detected was very low
  4. d Fisher's exact test
  5. e Mann Whitney U
  6. f Data on malaria was only available for those individuals who were analysed