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Table 1 Demographic and clinical characteristics compared by patients with and without M. tuberculosis (MTB) bacteremia

From: Blood cultures for the diagnosis of multidrug-resistant and extensively drug-resistant tuberculosis among HIV-infected patients from rural South Africa: a cross-sectional study

Characteristic

Total

n (%)

Blood culture positive for MTB, n (%)

Blood culture negative for MTB, n (%)

Bivariate relative risk [95% confidence interval],

p-value

Total

n = 130

n = 41

n = 89

 

Sex:

    

   Male

73 (56)

22 (54)

51 (57)

1.16 [0.55-2.4] p = 0.70

   Female

57 (44)

19 (46)

38 (43)

referent

Age range (years):

    

   0-14

8 (6)

1 (2)

7 (8)

0.42 [0.05-3.7] p = 0.43

   15-25

15 (11)

7 (17)

8 (9)

2.57 [0.81-8.2] p = 0.11

   26-35

67 (52)

17 (41)

50 (56)

referent

   36-45

28 (22)

11 (27)

17 (19)

1.9 [0.75-4.9] p = 0.18

   > 45

12 (9)

5 (12)

7 (8)

2.1 [0.59-7.5] p = 0.25

Prior history of TB treatment

    

   Yes

42 (32)

15 (37)

27 (30)

1.33 [0.61-2.9] p = 0.48

   No

88 (68)

26 (63)

62 (70)

referent

Currently on first-line TB treatment

    

   Yes

89 (69)

28 (68)

61 (69)

0.99 [0.45-2.2] p = 0.98

   No

41 (31)

13 (32)

28 (31)

referent

Duration of TB treatment for patients on treatment (median weeks)

[IQR]

8 [4.0-20.0]

10 [4.0-24]

8 [5.5-13.5]

p = 0.76

Clinical features extrapulmonary TB

    

   Yes

45 (35)

19 (46)

26 (29)

2.10 [0.97-4.5] p = 0.06

   No

85 (65)

22 (54)

63 (71)

referent

HIV status:

    

   Positive

114 (88)

34 (83)

80 (90)

p > 0.99

   Negative

1 (1)

0 (0)

1 (1)

referent

   Unknown

15 (11)

7 (17)

8 (9)

p > 0.99

CD4 counta (median cells/mm3)

[IQR]

100b [28-190]

92 [81-174]

104 [21-222]

p = 0.82

CD4 count cells/mm3

    

   0-100

32 (51)

24 (50)

8 (54)

1.92 [0.35-10.5] p = 0.45

   101-200

17 (27)

12 (25)

5 (33)

2.73 [0.44-17.1] p = 0.29

   > 200

14 (22)

12 (25)

2 (13)

referent

Receiving antiretroviral therapyc

    

   Yes

53 (47)

9 (26)

44 (55)

0.29 [0.12-0.71] p = 0.005

   No

61 (53)

25 (72)

36 (45)

referent

Duration of antiretroviral therapy(median weeks)

[IQR]

15 [4-31]

16 [7-32]

15 [5-30]

p = 0.92

  1. IQR = interquartile range.
  2. a Available in 63 (55%) of 114 HIV-infected patients.
  3. b CD4% in 3 pediatric cases (7.0%, 6.0% and 7.9%)
  4. cAvailable in 114 (100%) HIV-infected patients.