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Table 1 Demographic and clinical characteristics compared by patients with and without M. tuberculosis (MTB) bacteremia

From: Blood cultures for the diagnosis of multidrug-resistant and extensively drug-resistant tuberculosis among HIV-infected patients from rural South Africa: a cross-sectional study

Characteristic Total
n (%)
Blood culture positive for MTB, n (%) Blood culture negative for MTB, n (%) Bivariate relative risk [95% confidence interval],
p-value
Total n = 130 n = 41 n = 89  
Sex:     
   Male 73 (56) 22 (54) 51 (57) 1.16 [0.55-2.4] p = 0.70
   Female 57 (44) 19 (46) 38 (43) referent
Age range (years):     
   0-14 8 (6) 1 (2) 7 (8) 0.42 [0.05-3.7] p = 0.43
   15-25 15 (11) 7 (17) 8 (9) 2.57 [0.81-8.2] p = 0.11
   26-35 67 (52) 17 (41) 50 (56) referent
   36-45 28 (22) 11 (27) 17 (19) 1.9 [0.75-4.9] p = 0.18
   > 45 12 (9) 5 (12) 7 (8) 2.1 [0.59-7.5] p = 0.25
Prior history of TB treatment     
   Yes 42 (32) 15 (37) 27 (30) 1.33 [0.61-2.9] p = 0.48
   No 88 (68) 26 (63) 62 (70) referent
Currently on first-line TB treatment     
   Yes 89 (69) 28 (68) 61 (69) 0.99 [0.45-2.2] p = 0.98
   No 41 (31) 13 (32) 28 (31) referent
Duration of TB treatment for patients on treatment (median weeks)
[IQR]
8 [4.0-20.0] 10 [4.0-24] 8 [5.5-13.5] p = 0.76
Clinical features extrapulmonary TB     
   Yes 45 (35) 19 (46) 26 (29) 2.10 [0.97-4.5] p = 0.06
   No 85 (65) 22 (54) 63 (71) referent
HIV status:     
   Positive 114 (88) 34 (83) 80 (90) p > 0.99
   Negative 1 (1) 0 (0) 1 (1) referent
   Unknown 15 (11) 7 (17) 8 (9) p > 0.99
CD4 counta (median cells/mm3)
[IQR]
100b [28-190] 92 [81-174] 104 [21-222] p = 0.82
CD4 count cells/mm3     
   0-100 32 (51) 24 (50) 8 (54) 1.92 [0.35-10.5] p = 0.45
   101-200 17 (27) 12 (25) 5 (33) 2.73 [0.44-17.1] p = 0.29
   > 200 14 (22) 12 (25) 2 (13) referent
Receiving antiretroviral therapyc     
   Yes 53 (47) 9 (26) 44 (55) 0.29 [0.12-0.71] p = 0.005
   No 61 (53) 25 (72) 36 (45) referent
Duration of antiretroviral therapy(median weeks)
[IQR]
15 [4-31] 16 [7-32] 15 [5-30] p = 0.92
  1. IQR = interquartile range.
  2. a Available in 63 (55%) of 114 HIV-infected patients.
  3. b CD4% in 3 pediatric cases (7.0%, 6.0% and 7.9%)
  4. cAvailable in 114 (100%) HIV-infected patients.