Table 3 Estimated CD4 slope (cells/μL/year) by duration of treatment and HIV VL.
Month since cART initiation | HIV VL level (copies/mL) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | 500 | 1 000 | 2 000 | 3 000 | 4 000 | 5 000 | 10 000 | 20 000 | 30 000 | 40 000 | 50 000 | 100 000 | 150 000 |
|  | Patient 1, 30 years old, no hepatitis coinfection, no AIDS defining illness, and current CD4 200 cells per μL | ||||||||||||
6-12 | 85.6 | 73.4 | 61.2 | 54.1 | 49.0 | 45.1 | 32.9 | 20.7 | 13.6 | 8.5 | 4.6 | -7.6 | -14.7 |
12-18 | 64.1 | 51.9 | 39.7 | 32.6 | 27.5 | 23.6 | 11.4 | -0.8 | -7.9 | -13.0 | -16.9 | -29.1 | -36.2 |
18-24 | 59.8 | 47.6 | 35.4 | 28.3 | 23.2 | 19.3 | 7.1 | -5.1 | -12.2 | -17.3 | -21.2 | -33.4 | -40.5 |
24+ | 26.5 | 14.3 | 2.1 | -5.0 | -10.1 | -14.0 | -26.2 | -38.4 | -45.5 | -50.6 | -54.5 | -66.7 | -73.8 |
|  | Patient 2, 30 years old, coinfected with hepatitis, no AIDS defining illness, and current CD4 200 cells per μL | ||||||||||||
6-12 | 67.9 | 55.7 | 43.5 | 36.4 | 31.3 | 27.4 | 15.2 | 3.0 | -4.1 | -9.2 | -13.1 | -25.3 | -32.4 |
12-18 | 46.4 | 34.2 | 22.0 | 14.9 | 9.8 | 5.9 | -6.3 | -18.5 | -25.6 | -30.7 | -34.6 | -46.8 | -53.9 |
18-24 | 42.1 | 29.9 | 17.7 | 10.6 | 5.5 | 1.6 | -10.6 | -22.8 | -29.9 | -35.0 | -38.9 | -51.1 | -58.2 |
24+ | 8.8 | -3.4 | -15.6 | -22.7 | -27.8 | -31.7 | -43.9 | -56.1 | -63.2 | -68.3 | -72.2 | -84.4 | -91.5 |