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Table 1 Performance of line probe assay (LPA) in smear-positive sputum specimens compared with conventional drug susceptibility testing (MGIT DST)

From: Rapid screening of MDR-TB using molecular Line Probe Assay is feasible in Uganda

  

MGIT DST

    
  

INHR RIFR

INHR RIFS

INHS RIFR

INHS RIFS

No result*

LPA

INH R RIF R

12

3

0

0

4

 

INH R RIF S

0

6

0

0

0

 

INH S RIF R

1

0

2

1

2

 

INH S RIF S

0

4

0

63

15

 

Indeterminate

0

0

0

0

5

  1. LPA, line probe assay
  2. MGIT DST, Mycobacterial Growth Indicator Tube
  3. RIFS, rifampicin susceptible; RIFR, rifampicin resistant
  4. INHS, isoniazid susceptible; INHR, isoniazid resistant
  5. * No result was due to lack of growth from the frozen primary isolate (15), isolation of non-tuberculous mycobacteria (1), contamination (2) or unavailability of frozen isolate for MGIT DST (8).
  6. Indeterminate results included are those remaining without an interpretable result after repeat testing.