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Table 2 Characteristics and positivity rate of other HBV serological markers in HBsAg-negative HIV-seropositive patients in whom the occult HBV infection rate was investigated.

From: Occult Hepatitis B Virus infection in ART-Naive HIV-Infected Patients seen at a Tertiary Care Centre in North India

 

n

Anti-HBs and/or anti-HBc pos (%)

Anti-HBc pos

(%)

Anti-HBs pos

(%)

Only Anti-HBc pos

(%)

Only Anti-HBs pos

(%)

No HBV marker detected

(%)

Overall

53

24 (45.3)

19 (35.8)

11 (20.7)

13 (24.5)

5 (9.4)

29 (54.7)

Sex

       

Male

41

19 (46.3)

16 (39.0)

8 (19.5)

11 (26.8)

3 (7.3)

22 (53.6)

Female

12

5 (41.7)

3 (25)

3 (25)

2 (16.7)

2 (16.7)

7 (58.3)

Risk factors a

       

Heterosexual

46

20 (43.5)

16 (34.8)

8 (17.4)

12 (26.1)

4 (8.7)

26 (56.6)

Transfusion

3

2 (66.7)

1 (33.3)

2 (66.7)

0

1 (33.3)

1 (33.3)

IVDU

2

2 (100)

2 (100)

1 (50)

1 (50)

0

0

CD4 cell counts

       

≤ 200

35

15 (42.8)

12 (34.3)

4 (11.4)

11 (31.4)

3 (8.5)

20 (57.1)

201-499

12

7 (58.3)

5 (41.7)

6 (50)

1 (8.3)

2 (16.7)

5 (41.6)

≥ 500

6

2 (33.3)

2 (33.3)

1 (16.7)

1 (16.7)

0

4 (66.7)

ALT levels

       

Normal

30

14 (46.6)

11 (36.6)

8 (26.6)

6 (20)

4 (13.3)

16 (53.3)

Raised b

23

10 (43.4)

8 (34.7)

3 (13.0)

7 (30.4)

1 (4.3)

13 (56.5)

Other co-infections

       

HCV pos c

5

4 (80)

3 (60)

2 (40)

2 (40)

1 (20)

1 (20)

TB pos d

17

6 (35.3)

5 (29.4)

3 (17.6)

3 (17.6)

1 (5.9)

11 (64.7)

  1. Note: n, total no. tested; HCV, hepatitis C virus; TB, Mycobacterium tuberculosis; ALT, alanine aminotransferase; IVDU, injection drug use. Determined by Fisher's exact test for proportions
  2. a In 2 patients no risk factor could be ascertained.
  3. b Defined as serum ALT levels >40 IU/L
  4. c Determined by anti-HCV IgM antibodies
  5. d Diagnosis of tuberculosis was based on clinical suspicion, chest X-ray findings and sputum mycobacteriology