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Table 2 Prevalence and prevalence ratios of hepatic and extra-hepatic sequelae in HCV+ and HCV- by at-risk group, Lazio 1997-2001

From: Hepatic and extra-hepatic sequelae, and prevalence of viral hepatitis C infection estimated from routine data in at-risk groups

 

patients to dialysis†

drug users §

  

injector drug users §

 

HCV +

HCV -

ratio

95% CI

HCV +

HCV -

ratio

95% CI

HCV +

HCV -

ratio

95% CI

N

1107

7455

  

6009

23747

  

5755

18346

  

%

100

100

  

100

100

  

100

100

  

hepatic

120

451

  

447

382

  

427

309

  

diseases

10.4

6.1

1.8

1.5 - 2.2

7.4

1.6

4.6

4.0 - 5.3

7.4

1.7

4.4

3.8 - 5.1

Cirrhosis

48

95

  

389

266

  

370

218

  
 

4.3

1.3

3.4

2.4 - 4.9

6.5

1.1

5.8

4.9 - 6.8

6.4

1.2

5.4

4.6 - 6.4

Gastric

73

339

  

83

87

  

81

66

  

hemorrhage

0.3

4.6

1.5

1.1 - 1.9

1.4

0.4

3.8

2.8 - 5.1

1.4

0.4

3.9

2.8 - 5.5

Hemorrhage

            

due to eso-

3

13

  

25

12

  

13

10

  

phageal varix**

0.3

0.2

1.6

0.3 - 5.7

0.4

0.1

7.6

3.7 - 16.2

0.2

0.1

4.1

1.7 - 10.6

Liver failure

10

37

  

43

58

  

43

46

  
 

0.9

0.5

1.8

0.8 - 3.7

0.7

0.2

2.9

1.9 - 4.4

0.7

0.3

3.0

1.9 - 4.6

Hepato cellular

4

6

  

17

7

  

15

6

  

carcinoma

0.4

0.1

4.5

0.9 - 18.9

0.3

0.03

9.6

3.8 - 27.4

0.3

0.03

8.0

2.9 - 25.1

Hepatic

9

17

  

105

56

  

101

46

  

encephalopathy

0.8

0.2

3.6

1.4 - 8.5

1.7

0.2

7.4

5.3 - 10.4

1.8

0.3

7.0

4.9 - 10.1

Portal

5

6

  

27

22

  

24

18

  

hypertension

0.5

0.1

5.6

1.4 - 22.1

0.4

0.1

4.9

2.7 - 8.9

0.4

0.1

5.3

2.7 - 10.3

extra-hepatic

15

58

  

55

48

  

51

32

  

diseases

1.4

0.8

1.7

0.9 - 3.1

0.9

0.2

4.5

3.0 - 6.8

0.9

0.2

5.1

3.2 - 8.2

Cryoglobuli-

6

4

  

18

8

  

17

8

  

naemia††

0.6

0.1

10.1

2.4 - 48.7

0.3

0.03

8.9

3.7 - 23.6

0.3

0.04

6.8

2.8 - 18.1

Non-Hodgkin

2

14

  

25

19

  

23

15

  

lymphoma

0.2

0.2

1.0

0.1 - 4.2

0.4

0.1

5.2

2.8 - 10.0

0.4

0.1

4.9

2.4 - 10.1

         

female reproductive

 

transfusion

digestive system surgery

organs surgery

 

HCV +

HCV -

ratio

95% CI

HCV +

HCV -

ratio

95% CI

HCV +

HCV -

ratio

95% CI

N

1001

19840

  

7237

205746

  

1251

95293

  

%

100

100

  

100

100

  

100

100

  

hepatic

327

3418

  

2120

14661

  

65

506

  

diseases

32.7

17.2

1.9

1.7 - 2.1

29.3

7.1

4.1

3.9 - 4.3

5.2

0.5

9.8

7.4 - 12.7

Cirrhosis

245

996

  

1912

10031

  

48

137

  
 

24.5

5.0

4.9

4.2 - 5.6

26.4

4.9

5.4

5.2 - 5.7

3.8

0.1

26.7

18.8 - 37.3

Gastric

148

2585

  

358

4199

  

14

232

  

hemorrhage

14.8

13.0

1.1

1.0 - 1.3

5.0

2.0

2.4

2.2 - 2.7

1.1

0.2

4.6

2.5 - 7.9

Hemorrhage

            

due to eso-

75

292

  

236

942

  

5

16

  

phageal varix**

7.5

1.5

5.1

3.9 - 6.6

3.3

0.5

7.1

6.2 - 8.2

0.4

0.0

23.8

6.8 - 68.0

Liver failure

19

178

  

127

1597

  

7

137

  
 

1.9

0.9

2.1

1.2 - 3.4

1.8

0.8

2.3

1.9 - 2.7

0.6

0.1

3.9

1.5 - 8.2

Hepato cellular

40

157

  

468

1520

  

8

17

  

carcinoma

4.0

0.8

5.1

3.5 - 7.2

6.5

0.7

8.8

7.9 - 9.7

0.6

0.0

35.9

13.4 - 87.6

Hepatic

84

305

  

535

2374

  

6

33

  

encephalopathy

1.5

8.4

5.5

4.2 - 7.0

7.4

1.2

6.4

5.8 - 7.0

0.5

0.0

13.9

4.7 - 33.5

Portal

40

172

  

261

1220

  

5

15

  

hypertension

4.0

0.9

4.6

3.2 - 6.5

3.6

0.6

6.1

5.3 - 7.0

0.4

0.0

25.4

7.2 - 73.5

extra-hepatic

28

432

  

132

1465

  

24

601

  

diseases

2.8

2.2

1.3

0.8 - 1.9

1.8

0.7

2.6

2.1 - 3.1

1.9

0.6

3.0

1.9 - 4.6

Cryoglobuli-

9

17

  

54

87

  

6

9

  

naemia††

0.9

0.1

10.5

4.1 - 24.9

0.7

0.04

17.7

12.3 - 25.1

0.5

0.01

50.8

14.9 - 159

Non-Hodgkin

16

340

  

42

478

  

10

65

  

lymphoma

1.6

1.7

0.9

0.5 - 1.5

0.6

0.2

2.5

1.8 - 3.4

0.8

0.1

11.7

5.4 - 23.0

  1. HCV+ had laboratory confirmation of the infection; nc = not computable;
  2. † as reported in dialysis or hospital discharge registry;
  3. §as reported in drug users registry or in hospital discharge registry;
  4. **including syndromes due to both cirrhosis and portal hypertension.
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BMC Infectious Diseases

ISSN: 1471-2334

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