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Table 3 Associations between iron and inflammatory parameters and mortality among ART-naïve patients (n = 95) in Hasan Sadikin Hospital, September 2007 - August 2009

From: Anemia and iron homeostasis in a cohort of HIV-infected patients in Indonesia

   

Single

Multiple*

 

n

mortality

HR (95% CI)

p value

HR (95% CI)

p value

Ferritin

      

   Low-normal

31

4

1

 

1

 

   High

64

16

1.8 (0.6-5.4)

0.29

1.3 (0.4-4.6)

0.68

sTfR

      

   Normal-high

10

4

1

 

1

 

   Low

85

16

2.2 (0.7-6.6)

0.16

1.7 (0.5-5.3)

0.38

hsCRP

      

   < 50 mg/L

41

5

1

 

1

 

   > 50 mg/L

54

15

2.2 (0.1-6.1)

0.12

2.1 (0.6-7.3)

0.24

  1. *Cox proportional hazard models adjusted for CD4 cell count (< 50, > 50 cells/mm3), age (< 29, > 29 years old), anemia (no anemia Hb > 13 g/dl for men and > 12 g/dl for women, mild Hb < 10.5 - 12.99 g/dL for men; and < 10.5 - 11.99 g/dL for women, moderate-severe anemia: Hb < 10.5 g/dL), and gender.
  2. Ferritin: High > 400 ng/mL for men or > 150 ng/mL for women, low-normal < 400 ng/mL for men or < 150 ng/mL for women; sTfR: Low < 1870 U/mL; normal-high > 1870 U/mL
  3. HR, Hazard ration; CI: confidence interval; hsCRP, high sensitive C-reactive protein.