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Table 3 Significant differences in the clinical characteristics of patients with NNHCA-IE compared to community-acquired IE, as determined by multivariate analysis

From: Non-nosocomial healthcare-associated infective endocarditis in Taiwan: an underrecognized disease with poor outcome

 

NNHCA-IE

Community-

Univariate

Multivariate 1

 

n = 30

acquired IE

n = 148

OR (95%CI)

pvalue

OR (95%CI)

pvalue

Age ≧ 65 years, n (%)

19 (63.3)

27 (18.2)

7.7 (3.3-18.1)

< 0.001

  

Women, n (%)

13 (43.3)

28 (18.9)

3.3 (1.4-7.5)

0.004

  

Charlson comorbidity index ≧ 2 n (%)

27 (90.0)

27 (18.2)

40.3 (11.4-142.7)

< 0.001

27.5 (6.9-110.3)

< 0.001

Diabetes mellitus, n (%)

17 (56.7)

25 (16.9)

6.4 (2.8-14.9)

< 0.001

  

Hypertension, n (%)

20 (66.7)

26 (17.6)

9.4 (3.9-22.4)

< 0.001

7.5 (2.2-25.1)

0.001

Symptoms duration ≦ 7 days n (%)

25 (83.3)

95 (64.2)

2.8 (1.0-7.7)

0.041

  

Staphylococci infection, n (%)

23 (76.7)

75 (50.7)

3.2 (1.3-7.9)

0.009

  

MRSA infection, n (%)

13 (43.3)

14 (9.5)

7.3 (3.0-18.1)

< 0.001

12.2 (2.9-51.5)

0.001

Streptococci infection, n (%)

4 (13.3)

51 (34.5)

0.3 (0.1-0.9)

0.022

  
  1. 1 Adjusted for age and sex
  2. NNHCA-IE, non-nosocomial healthcare-associated infective endocarditis; OR, odds ratio; CI, confidence interval; MRSA, methicillin-resistant Staphylococcus aureus