Table 7 Study results of suppressive treatment of BV.
Cure rate after | |||||
|---|---|---|---|---|---|
Study | Treatment | >1 month | 3 months | 6 months | 12 months |
Sobel 1993 [50] | Oral metronidazole 7 days | 25% | |||
Topical clindamycin 7 days | 38% | ||||
Boris 1997* [28] | Oral metronidazole 10 days (for some 3 times) | 63% | |||
Eriksson 2005** [23] | Topical clindamycin 3 days + lactobacilli tampons | 57% | |||
Topical clindamycin 3 days + placebo tampons | 60% | ||||
Sobel 2006 [7] | 10 days vaginal metronidazole + twice weekly for 4 months | 43% | |||
10 days vaginal metronidazole + placebo | 19% | ||||
Bradshaw 2006 [6] | Oral metronidazole 7 days | 46% | 36% | 31% | |
Schwebke 2007 [51] | Metronidazole gel twice weekly for 6 months | 33% | |||
Marcone 2008 [29] | Oral metronidazole 7 days | 71% | 67% | ||
Oral metronidazole 7 days + Lactobacillus rhamnosus for 2 months | 88% | 83% | |||
Larsson 2008 [13] | Topical clindamycin 7 days + lactobacilli | 53% | |||
Topical clindamycin 7 days + placebo | 39% | ||||
Reichman 2009 [52] | Triple treatment with oral nitroimidazole | 65% | 50% | ||
21 days boric acid intravaginal and | |||||
Metronidazole gel 20 weeks (6 month treatment) | |||||
Ehrnström 2010 [37] | Vaginal clindamycin + 5 types of lactobacilli | 50% | |||
Marcone 2010 [30] | Oral metronidazole 7 days | 74% | 69% | ||
Oral metronidazole 7 days + Lactobacillus rhamnosus for 6 months | 96% | 91% | |||
This study | Oral and vaginal clindamycin + vaginal metronidazole + lactobacilli | 74.6% | 65.1% | ||
*Only cured patients were followed and some were treated 3 times. | |||||