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Table 1 Co-infections (viral, bacterial, fungal; culture-confirmed) in children with severe seasonal influenza - Germany, 2005-2008 *

From: Severe influenza cases in paediatric intensive care units in Germany during the pre-pandemic seasons 2005 to 2008

Co-infection

Infectious agent

Diagnostics/material

No. of children (%)

Viral

Respiratory Syncytial Virus (RSV)

RSV-test (antigen, PCR, or immunofluorescence)

4 (20)

Bacterial - gram positive

Staphylococcus aureus

Pleural fluid (1), tracheal aspirate (2)

3 (15)

 

Staphylococcus epidermis

Blood culture

2 (10)

 

Staphylococcus hominis

Blood culture

1 (5)

 

Streptococcus pneumoniae

Liquor and brain tissue (post-mortem)

1 (5)

 

Enterococcus sp.

Central venous catheter/blood culture

1 (5)

Bacterial - gram negative

Hafnia alvei

Tracheal aspirate

1 (5)

Bacterial - mycoplasma-like

Mycoplasma pneumoniae.

Serology

1 (5)

Fungal

Candida albicans

Tube tip

1 (5)

 

Aspergillus sp.

Tracheal aspirate

1 (5)

  1. * Data on co-infections reported in 13 (65%) of 20 children; percentages refer to the number of all 20 patients. Multiple nominations were possible. sp: species; not further specified