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Table 1 Demographic data of the multidrug-resistant tuberculosis patients with or without pyrazinamide (PZA) resistancea

From: Characteristics of pncA mutations in multidrug-resistant tuberculosis in Taiwan

 

PZA susceptibility test

P value

 

Resistant, n = 36

Susceptible, n = 30

 

Age (MD)

58.3 (21.0)

57.8 (17.8)

0.91

Gender

   

   Male

25 (69.4%)

24 (80%)

0.33

   Female

11 (30.6%)

6 (20%)

 

Previous anti-TB treatment

   

   Yes

11 (30.6%)

10 (33.3%)

0.81

   No

25 (69.4%)

20 (66.7%)

 

Sputum smear

   

   Positive

17 (47.2%)

22 (73.3%)

0.032

   Negative

19 (52.8%)

8 (26.7%)

 

Disease site

   

   Pulmonary TB

35 (97.2%)

28 (93.3%)

0.45

   Extrapulmonary TB

1 (2.8%)

2 (6.7%)

 

Presence of cavity in radiogram

   

   Yes

8 (22.2%)

12 (40%)

0.12

   No

28 (77.8%)

18 (60%)

 

Ethambutol resistance

   

   Yes

21 (58.3%)

10 (33.3%)

0.043

   No

15 (41.7%)

20 (66.7%)

 

Streptomycin resistance

   

   Yes

24 (66.7%)

11 (36.7%)

0.015

   No

12 (33.3%)

19 (63.3%)

 

Genotyping

   

   Beijing strain

21 (58.3%)

16 (53.3%)

0.68

   Non-Beijing strain

15 (41.7%)

14 (46.7%)

 
  1. aData are presented as n(%) unless otherwise stated.