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Table 3 Competing risks regression analysis of time from TB diagnosis to start of antiretroviral therapy (ART) for all patients with CD4 cell count measurements (n = 789)

From: Delays in starting antiretroviral therapy in patients with HIV-associated tuberculosis accessing non-integrated clinical services in a South African township

Patient characteristics

Crude SHR1

95% CI

P value1

Adjusted SHR

95% CI

P value2

Age category

  

0.514

   

   18-24

1.06

0.83-1.36

0.617

   

   25-39

1.10

0.93-1.31

0.251

   

   ≥40

1

     

Gender

      

   Female

1.03

0.89-1.19

0.717

   

   Male

1

     

Calendar period

  

0.022

  

0.013

   Jul 2002 - Aug 2005

1

  

1

  

   Sept 2005 - Aug 2006

1.20

1.03-1.41

0.019

1.26

1.05-1.51

0.013

   Sept 2006 - Jan 2008

1.21

1.02-1.45

0.033

1.26

1.04-1.53

0.016

CD4 cell count

  

< 0.001

  

0.001

   ≥200

1

  

1

  

   100-199

1.65

1.29-2.11

< 0.001

1.46

1.13-1.88

0.004

   50-99

1.92

1.48-2.49

< 0.001

1.83

1.40-2.38

< 0.001

   0-49

1.96

1.50-2.54

< 0.001

1.71

1.30-2.26

< 0.001

TB classification

      

   Retreatment case

1

     

   New case

1.04

0.9-1.21

0.586

   

Type of TB

  

< 0.001

  

< 0.001

   Smear-negative PTB

1

  

1

  

   EPTB

1.50

1.26-1.79

< 0.001

1.44

1.17-1.76

0.001

   Smear-positive PTB

2.82

2.37-3.37

< 0.001

2.49

2.04-3.04

< 0.001

Place of TB diagnosis

      

   TB clinic

1

  

1

  

   ART clinic

1.91

1.54-2.37

< 0.001

1.88

1.51-2.34

< 0.001

  1. 1 SHR = sub-hazard ratio. Higher ratios denote more rapid initiation of ART.
  2. 2 P values in line with the heading of each variable with more than two categories were calculated using the Wald test.