In-vitroanalysis of the microbicidal activity of 6 contact lens care solutions

BMC Infectious Diseases

Table 4 Proportions of reduction factors exceeding pre-specified thresholds for each CL care solution and for each tested microorganism / complete data set

	S. aureus				P. aeruginosa				S. marcescens				C. albicans				F. solani
	RF ≥ 3		RF ≥ 5		RF ≥ 3		RF ≥ 5		RF ≥ 3		RF ≥ 5		RF ≥ 1		RF ≥ 4		RF ≥ 1		RF ≥ 4
	%	N	%	N	%	N	%	N	%	N	%	N	%	N	%	N	%	N	%	N
AOSEPT PLUS	88.9	18	77.8	18	100	12	100	12	88.9	18	66.7	18	100	12	100	12	100	12	100	12
BlueVision	61.1	18	22.2	18	100	12	100	12	100	12	100	12	100	12	100	12	100	12	100	12
Easy Sept	11.1	18	0	18	100	12	100	12	100	12	100	12	100	12	100	12	100	12	100	12
Oxysept Comfort	0	12	0	12	100	12	100	12	100	12	100	12	100	12	100	12	100	12	100	12
Optifree Replenish	61.1	18	0	18	94.4	18	83.3	18	95.8	24	20.8	24	94.4	18	16.7	18	95.8	24	87.5	24
Solocare Aqua	0	18	0	18	38.9	18	11.1	18	0	12	0	12	77.8	18	22.2	18	100	24	58.3	24
χ ² test	< 0.001		< 0.001		< 0.001		< 0.001		< 0.001		< 0.001		0.041		< 0.001		0.695		< 0.001

The intervals ≥ 3.0 log [CFU/ml] for bacteria and ≥ 1.0 log [CFU/ml] for fungi were assessed according to the criteria of the EN ISO 14729 Stand Alone Test [47]. The intervals ≥ 5.0 log [CFU/ml] for bacteria according to the criteria of the norms EN 1040 [58], EN 13727 [59] and EN 1276 [60] and ≥ 4.0 log [CFU/ml] for fungi according to the criteria of the norms EN 1275 [61], EN 13624 [62] and EN 1650 [63] were assessed.

ISSN: 1471-2334