Skip to main content

Table 2 Patient’s clinical characteristics on the day of infection (D0), PCT kinetics the previous 4 days until D0 and diagnostic criteria for CRBSI

From: Procalcitonin and procalcitonin kinetics for diagnosis and prognosis of intravascular catheter-related bloodstream infections in selected critically ill patients: a prospective observational study

 

Not proven CRBSI

Proven CRBSI

P

 

n = 20

   n = 26

 

Time elapsed from ICU admission [days; mean (SD)]

10.70 (2.62)

11.77 (3.31)

0.242a

Catheter in place [days; mean (SD)]

8.25 (1.41)

8.73 (2.05)

0.375a

Presence of SIRS [no (%)]

20 (100)

26 (100)

1.0 b

WBC count 10 3/μl; mean (SD)]

14.68 (3.8)

15.37 (6.03)

0.658a

CRP [mg/dl; median (IQR)]

12.75 (7.93-18.33)

15.78 (10.59-21.48)

0.236c

SOFA score [mean (SD)]

5.85 (2.41)

7.19 (2.70)

0.087a

Shock [no (%)]

9 (45.0)

14 (53.8)

0.552b

PCT [ng/ml; median (IQR)]

D-4 (20/26) d

0.15 (0.10-0.20)

0.20 (0.10-0.50)

0.289c

D-3 (20/26) d

0.10 (0.10-0.28)

0.25 (0.10-0.63)

0.017c

D-2 (20/26) d

0.10 (0.10-0.20)

0.50 (0.20-1.40)

<0.001c

D-1 (20/26) d

0.10 (0.10-0.30)

0.75 (0.40-2.50)

<0.001c

D0 (20/26) d

0.10 (0.10-0.27)

7.70 (2.50-11.43)

<0.001c

ΔPCTD-4, D0

0.00 (−0.90-0.40)

7.05 (2.40-10.43)

<0.001c

ΔPCTD-3, D0

0.00 (−0.90-0.40)

6.45 (2.40-10.30)

<0.001c

ΔPCTD-2, D0

0.00 (−0.60-0.40)

5.55 (2.23-9.93)

<0.001c

ΔPCTD-1, D0

0.00 (−0.40-0.10)

4.85 (1.00-9.28)

<0.001c

Diagnosis of CRBSI

   

Criterion 1 [no (%)]

_

6 (23.1)

 

Criterion 2 [no (%)]

_

10 (38.5)

 

Both criteria (1 + 2) [no (%)]

_

10 (38.5)

 
  1. a Student’s t test; b Chi-square test; c Mann–Whitney test; d No of patients available for analysis (Not proven/proven).