Table 1 Characteristics of children at the time of enrollment (N=2649)
Characteristic | Year of surveillance | P | |||
|---|---|---|---|---|---|
| Â | 2005 | 2006 | 2007 | 2009 | Â |
Time-period of enrollment | February 28 to June 7 | February 2 to April 13 | February 26 to May 17 | February 24 to May 19 | Â |
 PCV7 in the National Immunization Program | -- | + | + | + |  |
 PCV7 reimbursed | -- | -- | + | + |  |
No. of enrolled children | 769 | 494 | 566 | 820 | Â |
Age, median (range), months | 49 (15–76) | 46.5 (13–70) | 46 (13–73) | 48 (14–72) | — |
Male gender | 417 (54.2)a | 248 (50.2) | 297 (52.5) | 427 (52.1) | 0.529 |
Antibiotic use in the preceding 3 months | 433/764b (56.7) | 260/489 (53.2) | 284/566 (50.2) | 459/818 (56.1) | 0.647 |
Vaccinated with ≥1 dose of PCV7 | 99 (12.9) | 161 (32.6) | 397 (70.1) | 783 (95.5) | <0.001 |
 Age-appropriately vaccinated | 92 (12) | 150 (30.4) | 351 (62) | 668 (81.5) | <0.001 |
Streptococcus pneumoniae carriage | Â | Â | Â | Â | Â |
  per age-group, months |  |  |  |  |  |
 13 − 23 | 12/21 (57.1) | 11/22 (50) | 18/26 (69.2) | 13/18 (72.2) | 0.176 |
 24 – 35 | 74/121 (61.2) | 34/69 (49.3) | 50/99 (50.5) | 43/100 (43) | 0.01 |
 36 – 47 | 130/231 (56.3) | 78/185 (42.2) | 84/183 (45.9) | 118/279 (42.3) | 0.006 |
 48 – 59 | 101/240 (42.1) | 70/188 (37.2) | 109/208 (52.4) | 132/349 (37.8) | 0.721 |
 ≥60 | 53/156 (34) | 13/30 (43.3) | 25/50 (50) | 28/74 (37.8) | 0.273 |
 Overall | 370 (48.1) | 206 (41.7) | 286 (50.5) | 334 (40.7) | 0.036 |