Table 2 Summary of histopathological findings
Feature | Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 |
|---|---|---|---|---|---|
Hepatocytes | |||||
Swelling | mild | marked | mild | mild | marked |
Regeneration | Present | Present | Present | Present | Present |
Steatosis | Patchy | Diffuse | Patchy | Patchy | Diffuse |
Cholestasis | Present | Present | Present | Present | Present |
Inflammation | |||||
NGI | Portal/parenchymal | Portal/parenchymal | Portal/parenchymal | Absent | Absent |
NNGI | Portal/parenchymal | Portal/parenchymal | Portal/parenchymal | Absent | Absent |
Langhans GC | NGI/NNGI | NGI/NNGI | NGI/NNGI | Absent | Absent |
NPs | NGI | NGI & parenchyma | NGI | parenchyma | *portal tracts & parenchyma |
LCs | Portal/parenchymal; T dominant (admixed CD4+/CD8+) | Portal/parenchymal; T dominant (admixed CD4+/CD8+) | Portal/parenchymal; T dominant (admixed CD4+/CD8+) | nil | Portal/parenchymal; T dominant (dominant CD8+) |
PCs | Portal | Portal | Portal & parenchymal | nil | Portal & parenchymal |
EPs | Portal/parenchymal | Portal/parenchymal | Portal/parenchymal | nil | *Portal/parenchymal |
HCs | Portal/parenchymal | Portal/parenchymal | Portal/parenchymal | nil | Portal/parenchymal |
Other | |||||
Architecture | Maintained | Mixed cirrhosis | Maintained | Cannot comment | Maintained |
Fibrosis | Portal | Fibrous linkages | Portal | Cannot comment | nil |
I/hepatitis | Absent | Absent | Absent | Cannot comment | Present |
ZN | Paucibacillary | Negative | Negative | Not done- no tissue | Negative |
PCR | Positive | Positive | Positive | Not done – no tissue | Negative |
Haemosiderin | Present | Present | Present | Present | Present |