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Table 1 Characteristics of the controls and patients with laboratory-confirmed, hospital-acquired influenza (HAI) and of the factors associated with HAI in Edouard Herriot Hospital, Lyon (France), in influenza seasons 2004-05, 2005-06 and 2006-07

From: Influenza vaccination of healthcare workers in acute-care hospitals: a case-control study of its effect on hospital-acquired influenza among patients

Characteristics

Patients with confirmed HAI (N = 11)

Controls (N = 44)

P

Crude ORa (95% CI)

Gender, female

8 (73)

33 (75)

1.0

0.89 (0.22-3.72)

Age, years

   

0.99 (0.97-1.02)b

   Median (range)

66.0 (48.5-85.1)

78.7 (42.3-86.7)

0.6

 

Type of ward

  

1.0

 

   Medicine

8 (73)

31 (70)

 

1.0 (Ref.)

   Surgery

3 (27)

13 (30)

 

0.90 (0.21-3.89)

Chronic pulmonary disease

2 (18)

5 (11)

0.6

1.60 (0.31-8.25)

Chronic cardiac disease

5 (45)

21 (48)

1.0

0.92 (0.26-3.28)

Immuno-depression

2 (18)

1 (2)

0.10

8.00 (0.73-88.22)

Potential influenza source in the unitc

7 (64)

13 (30)

0.08

4.06 (1.08-15.33)

Individual influenza vaccinationd, e

2 (20)

21 (48)

0.16

0.34 (0.069-1.70)

Proportion of vaccinated HCW in the unit

  

0.10

 

   < 35%

8 (73)

19 (43)

 

1.0 (Ref.)

   ≥ 35%

3 (27)

25 (57)

 

0.16 (0.018-1.32)

  1. Data are reported as numbers (%) under descriptive analysis and as OR (95% CI) under logistic regression analysis. Controls were hospitalised patients with ILI and confirmed exclusion of influenza diagnosis after nasal swabbing; they were matched by influenza season (2004-05, 2005-06 and 2006-07). HAI, hospital-acquired influenza; OR, odds ratio; CI, confidence interval; HCW, healthcare workers.
  2. aUnder univariate conditional logistic regression
  3. bPer 1 year older
  4. cPotential sources of exposure to influenza (other patients or HCW) for 5 days before ILI or influenza occurrence in the same ward
  5. dIn current influenza season
  6. eIndividual influenza vaccination was not known in 1 patient