Number of damaged regions based on mean-to-median ratio. Images with a mean-to-median ratio were enumerated per animal and averaged within treatment groups. No statistical significance occurred between PBS and HEC cases. Statistically significant increase in the number of damaged regions occurred with 0.02% BZK, 0.2% BZK, and N-9. Results in the 0.02% BZK case were similar to N-9, and both were statistically different from those at 0.2% BZK. Statistical analysis for comparison between treatment groups was by single factor ANOVA followed by Tukey's post hoc test for significance. Statistical significance with p < 0.05 is represented with * and p <0.01 with **.