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Table 1 Demographic characteristics, univariable analysis between patients with ICU fungal HAIs and patients without ICU HAIs

From: A risk factor analysis of healthcare-associated fungal infections in an intensive care unit: a retrospective cohort study

Variables

No HAI

Fungal HAI

pvalue

n = 1674(%)

n = 186(%)

Age, years mean ± SD,

67.5 ± 18.0

71.6 ± 16.0

0.001

APACHE II score, mean ± SD

22.5 ± 7.6

24.7 ± 7.0

<0.001

ICU stay before infection, mean ± SD

6.9 ± 5.7

9.8 ± 7.1

<0.001

Length of ICU stay, mean ± SD

6.9 ± 5.7

20.9 ± 14.7

<0.001

Total parenteral nutrition use before infection, days, mean ± SD

6.9 ± 6.7

19.2 ± 1.7

<0.001

Total parenteral nutrition use (yes)

44(2.6)

36(19.4)

<0.001

Gender (male)

1192(71.2)

131(70.4)

0.865

Service (surgical)

643(38.4)

105(56.5)

<0.001

Main diagnosis(yes)

   

 Neoplasms

356(21.3)

40(21.5)

0.939

 Digestive system

334(20.0)

54(29.0)

0.003

 Respiratory system

272(16.2)

21(11.3)

0.078

 Genitourinary system

174(10.4)

14(7.5)

0.218

 Sepsis

51(3.0)

13(69.9)

0.005

7days before fungal infection with antibiotic therapy

1042(62.2)

141(75.8)

<0.001

Mortality in ICU

305 (18.2)

56 (30.1)

<0.001

Invasive procedures (yes)

   

Central venous catheter

1550(92.6)

178(95.7)

<0.001

Mechanical ventilator

1139(68.0)

148(79.6)

0.001

Urinary catheter

854(51.0)

123(66.1)

<0.001

Wound drainage

1550(92.6)

178(95.7)

<0.001

Hemodialysis

417(24.9)

65(34.9)

0.003

  1. SD, Standard deviation; APACHE, Acute Physiology and Chronic Health Evaluation; ICU, intensive care unit; HAI, healthcare-associated infection.