Table 1 Characteristics of HIV positive patients who attended King’s College Hospital, London, UK between January 2000 and December 2009
Characteristics at cohort entry1,2 | All patients (n = 2751) | ICU admission (n = 118) | No ICU admission (n = 2633) | P value |
|---|---|---|---|---|
Age at diagnosis (mean, SD) | 35.2 (9.4) | 38.4 (9.7) | 35.0 (9.3) | 0.002 |
Female sex | 1183 (43) | 75 (64) | 1108 (42) | <0.0001 |
Black ethnicity | 1710 (62) | 76 (65) | 1634 (62) | 0.57 |
HIV exposure risk factor | 0.001 | |||
Heterosexual | 1645 (60) | 77 (69) | 1568 (60) | |
Homosexual | 739 (27) | 22 (20) | 717 (27) | |
IVDU | 132 (5) | 11 (10) | 121 (5) | |
Hepatitis B surface antigen positive | 134 (7) | 12 (12) | 122 (7) | 0.04 |
Hepatitis C antibody positive | 196 (9) | 7 (7) | 189 (9) | 0.54 |
AIDS diagnosis3 | 554 (22) | 58 (50) | 493(19) | 0.0001 |
CD4 cell count (median, IQR) | 302 (134, 472) | 70 (21, 207) | 312 (148, 482) | <0.001 |
Late HIV diagnosis | 1410 (59) | 96 (89) | 1314 (58) | <0.0001 |
Advanced HIV disease | 810 (34) | 79 (73) | 731 (32) | <0.0001 |
Characteristics of ICU patients 1,4,5 | ||||
CD4 cell count (median, IQR) | 81 (21, 191) | |||
Receiving cART | 47 (39) | |||
HIV RNA <400 c/mL | 20 (21) | |||
APACHE2 score (median, IQR) | 23 (17, 28) | |||
Opportunistic infection6 | 54 (46) | |||
Non-opportunistic infection6 | 19 (16) | |||
Malignancy6 | 13 (11) | |||
Liver disease6 | 6 (5) | |||
Neurological disease6 | 5 (4) | |||
Other6 | 21 (17) |