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Table 2 Correlation of detected mutations in the rrs and eis genes with phenotypic DST

From: Detection of second-line drug resistance in Mycobacterium tuberculosis using oligonucleotide microarrays

Gene (mutation)

No. of isolates

MIC Bactec MGIT 960 (mg/L)

KAN

CAP

rrs (a1401g)

17

>80

3-20

eis (g-10a)

10

5 to >80

0.6 to 2.5

eis (c-12t)

2

1.3 to 5

1.3

eis (c-14t)

2

20

1.3

1

0.63

1.3

eis (g-37t)

3

10 to 20

1.3 to 2.5

No mutation

29

0.3 to 2.5

0.6 to 2.5

1

5

1.3

(H37Rv)

2.5

2.5

  1. The MICs considered to reflect resistance are highlighted in bold.