Detection of second-line drug resistance in Mycobacterium tuberculosis using oligonucleotide microarrays

Table 4 Performance of biochips in comparison with DST

Biochip result^a	Number of isolates with the indicated result
	OFX		LVX		MFX		KAN		CAP^b		XDR
	R	S	R	S	R	S	R	S	R	S	R	S
R	41	0	24	17	40	1	33	2	16	1	26	2
S	1	23	0	24	0	24	1	29	0	48	2	37
Sensitivity (%)	98		100		100		97		100		93
Specificity (%)	100		59		98		94		94		95

^a - R, isolates with mutations in gyrA, gyrB (FQ), rrs(KAN and CAP), eis(KAN); S, isolates without mutations.
^b - Isolates with mutations in eis were considered sensitive in biochip analysis.