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Table 3 Annual prevalence of reactive syphilis results among HIV-positive participants in the OHTN Cohort Study, 2000-09

From: Patterns of syphilis testing in a large cohort of HIV patients in Ontario, Canada, 2000–2009

 

N under observation

Not tested

Non-reactive

Reactive

Reactive & acute (a)

  

N

%

N

%

N

%

N

%

MSM

         

2000

1139

1108

97.3

19

1.7

6

0.5

1

0.1

2001

1076

1019

94.7

35

3.3

4

0.4

1

0.1

2002

1093

1006

92.0

67

6.1

12

1.1

5

0.5

2003

1050

927

88.3

83

7.9

36

3.4

15

1.4

2004

1114

899

80.7

162

14.5

47

4.2

17

1.5

2005

1101

708

64.3

330

30.0

61

5.5

15

1.4

2006

1066

576

54.0

384

36.0

100

9.4

12

1.1

2007

1071

575

53.7

392

36.6

103

9.6

7

0.7

2008

1893

1007

53.2

631

33.3

246

13.0

47

2.5

2009

2309

988

42.8

918

39.8

400

17.3

88

3.8

P-value for time trend

   

P < 0.0001

P < 0.0001

Non-MSM Males

        

2000

254

247

97.2

5

2.0

1

0.4

0

0

2001

245

226

92.2

14

5.7

2

0.8

0

0

2002

253

239

94.5

11

4.3

3

1.2

1

0.4

2003

246

231

93.9

11

4.5

4

1.6

1

0.4

2004

266

238

89.5

28

10.5

0

0

0

0

2005

262

192

73.3

67

25.6

3

1.1

0

0

2006

255

170

66.7

75

29.4

10

3.9

1

0.4

2007

259

165

63.7

84

32.4

10

3.9

0

0

2008

388

274

70.6

102

26.3

12

3.1

0

0

2009

449

244

54.3

192

42.8

11

2.4

0

0

P-value for time trend

   

P = 0.0002

P = 0.4443

Females

         

2000

197

191

97.0

5

2.5

0

0

0

0

2001

190

177

93.2

10

5.3

0

0

0

0

2002

208

189

90.9

19

9.1

0

0

0

0

2003

201

189

94.0

12

6.0

0

0

0

0

2004

226

200

88.5

26

11.5

0

0

0

0

2005

225

166

73.8

59

26.2

0

0

0

0

2006

233

142

60.9

89

38.2

1

0.4

0

0

2007

238

149

62.6

88

37.0

1

0.4

0

0

2008

425

293

68.9

125

29.4

7

1.6

0

0

2009

499

254

50.9

234

46.9

11

2.2

0

0

P-value for time trend

   

P < 0.0001

n/a

  1. Percentages shown are row percents. For participants who underwent testing more than once in a single calendar year and had both reactive and non-reactive results, we classified their results as reactive. P-values for calendar year time trends were calculated using logistic regression with GEE.
  2. (a) Acute reactive results were defined as a reactive trepomenal test and RPR titre greater than or equal to 1:16.