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Figure 4 | BMC Infectious Diseases

Figure 4

From: MicroRNA regulation and its effects on cellular transcriptome in Human Immunodeficiency Virus-1 (HIV-1) infected individuals with distinct viral load and CD4 cell counts

Figure 4

Predicted interaction networks of genes significantly dysregulated in HVL compared to Control. (A) The interactions between genes were identified using STRING software. Colored lines indicate different sources of evidence for each interaction. Circles highlight the predominant clusters within the network. (B & C) Gene Ontology Enrichment analysis for biological processes using significantly differentially regulated genes in LVL and HVL groups in comparison with CT group. Genes that are differentially regulated in LVL group relative to the CT yielded 4 significant terms for biological processes (B), while those that are differentially regulated in HVL with respect to CT yielded 34 (C). Bar graphs are generated using average –lop of p value for each term on y-axis and term name on x-axis. CT, uninfected control; LVL, low viral load group; HVL, high viral load group.

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