MicroRNA regulation and its effects on cellular transcriptome in Human Immunodeficiency Virus-1 (HIV-1) infected individuals with distinct viral load and CD4 cell counts

Table 1 Differentially regulated miRNA in low and high viral load groups compared to uninfected control group using two different software with statistical significance

	Differentially regulated miRNA+/- 2-fold p < 0.05			Differentially regulated miRNA+/- 2-fold p < 0.01
	DataAssist	StatMiner	Common	DataAssist	StatMiner	Common
Control vs. LVL	38	41	21	8	14	8
Control vs. HVL	244	218	191	163	137	118
LVL vs. HVL	183	182	158	90	99	80

Comparative analysis of significantly differentially regulated miRNAs between Statminer (Integromics) and DataAssist (Applied Biosystems). For both analyses, RNU44, RNU48, and ath-miR-159 controls were eliminated from the analysis. For DataAssist, all miRNAs with CT valve of <40 were considered.

ISSN: 1471-2334