Table 2 Characteristics of patients in TDF+PI/r and control groups at the end of 48 weeeks ^a

BMI ^b (kg/m ² )

21.9 (20.1-23.7)

21.0 (19.3-22.9)

0.083

CD4 cell count (cells/μl)

279 (196–380.5)

292.0 (207.0-394.0)

0.736

Viral load (log ₁₀ copies/ml)

1.6 (1.6-1.8)

1.6 (1.6-1.7)

0.064

Proteinuria

0.071

  Positive

9 (12)

3(4)

  Negative

66 (88)

72 (96)

Serum creatinine (μmol/L)

79 (70–85)

69.7 (62–80.3)

<0.001

eGFR ^c (ml/min/1.73 m ² )

93.0 (82.4-104.0)

101.6 (86.8-121.6)

0.009

Change in eGFR (ml/min/1.73 m ² )

−8.8(−18.5-3.3)

6.4(−3.8-16.5)

<0.001