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Table 1 Pre-index demographic and clinical characteristics

From: Association of RSV-related hospitalization and non-compliance with Palivizumab among commercially insured infants: a retrospective claims analysis

Demographic

 

Total

Compliant

Non-compliant

p-value

  

(N = 5,003)

(N = 1,912)

(N = 3,091)

 

Gender

Male

n

2,738

1,046

1,692

 
 

%

54.73

54.71

54.74

0.982

Birth Number

All stillborn siblings

n

25

9

16

 
 

%

0.5

0.47

0.52

0.819

Single birth

n

2,857

1,049

1,808

 
 

%

57.11

54.86

58.49

0.012

Twin

n

1,427

599

828

 
 

%

28.52

31.33

26.79

<0.001

Multiple birth

n

256

115

141

 
 

%

5.12

6.01

4.56

0.023

Other

n

4

1

3

 
 

%

0.08

0.05

0.1

0.586

Not available

n

434

139

295

 
 

%

8.67

7.27

9.54

0.005

Clinical Characteristics

Low birth weight (<2500 g)

n

3,337

1,337

2,000

 
 

%

66.7

69.93

64.7

<0.001

<33 wGA

n

1,895

755

1,140

 
 

%

37.8

39.5

36.9

0.065

33-36 wGA

n

2,201

854

1,347

 
 

%

44

44.7

43.6

0.452

NICU

NICU hospitalization

n

3,830

1,523

2,307

 
 

%

86.79

88.19

85.89

0.028

NICU hospitalization length

n

4,413

1,727

2,686

 
 

mean

15.79

15.93

15.7

0.714

 

SD

20.38

20.23

20.48

 
 

median

8

8

8

 

Birth Hospitalization

Length of birth hospitalization

n

4,413

1,727

2,686

 
 

mean

25.4

26.15

24.92

0.062

 

SD

21.44

20.98

21.72

 
 

median

19.00

20.00

18.00

 

Comorbidity

Immunodeficiency state

n

23

3

20

 
 

%

0.46

0.16

0.65

0.013

Trisomy 21

n

119

44

75

 
 

%

2.38

2.3

2.43

0.778

Intraventricular hemorrhage

n

397

158

239

 
 

%

7.94

8.26

7.73

0.499

Necrotizing enterocolitis

n

114

35

79

 
 

%

2.28

1.83

2.56

0.095

Hydrocephalus

n

56

19

37

 
 

%

1.12

0.99

1.2

0.507

Periventricular leukomalacia

n

54

21

33

 
 

%

1.08

1.1

1.07

0.919

Retinopathy of prematurity

n

1,206

452

754

 
 

%

24.11

23.64

24.39

0.545

Sensorineural hearing loss

n

66

20

46

 
 

%

1.32

1.05

1.49

0.183

Severe neuromuscular disorders

n

127

48

79

 
 

%

2.54

2.51

2.56

0.921

Cerebral palsy

n

12

3

9

 
 

%

0.24

0.16

0.29

0.345

Cystic fibrosis

n

60

30

30

 
 

%

1.2

1.57

0.97

0.059

CMV

n

8

0

8

 
 

%

0.16

0

0.26

0.026

Chromosomal syndrome

n

168

58

110

 
 

%

3.36

3.03

3.56

0.316

Congenital anomalies of the airways

n

192

65

127

 
 

%

3.84

3.4

4.11

0.205

Pre-index home medical equipment

n

1,449

548

901

 
 

%

28.96

28.66

29.15

0.712

Post-index home medical equipment

n

1,115

430

685

 
 

%

22.29

22.49

22.16

0.786

Oxygen use

n

392

144

248

 
 

%

7.84

7.53

8.02

0.529