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Table 3 Antimicrobial resistance among the most relevant aetiologies of community-onset bloodstream infections in community-acquired and healthcare-related episodes

From: Reappraisal of the outcome of healthcare-associated and community-acquired bacteramia: a prospective cohort study

 

CA episodes

HCA episodes

P value

Escherichia coli

N = 57

N = 71

 

  Amoxicillin-clavulanic acid-resistant

9 (15.7)

9 (12.6)

0.61

  Cefotaxime-resistant1

5 (8.7)

6 (8.4)

0.94

  Ciprofloxacin-resistant

14 (24.5)

26 (36.6)

0.14

  Gentamycin-resistant

2 (3.5)

5 (7.0)

0.46

  Any resistance

15 (26.3)

25 (35.2)

0.33

Klebsiella spp.

N = 12

N = 13

 

  Amoxicillin-clavulanic acid-resistant

2 (16.6)

4 (30.7)

0.64

  Cefotaxime-resistant1

1 (8.3)

1 (7.6)

1.0

  Ciprofloxacin-resistant

0

1 (7.6)

1.0

  Gentamycin-resistant

0

2 (15.3)

0.48

  Any resistance

2 (16.6)

3 (23.0)

1.0

Pseudomonas aeruginosa

N = 1

N = 13

 

  Ceftazidime-resistant

0

1 (7.6)

-

  Imipenem-resistant

0

2 (15.3)

-

  Ciprofloxacin-resistant

0

2 (15.3)

-

  Amikacin-resistant

0

0

-

Streptococcus pneumoniae

N = 27

N = 11

 

  Penicillin-resistant

2 (7.4)

5 (45.4)

0.01

  Erithromycin-resistant

2 (7.4)

1 (9.0)

0.56

  Levofloxacin-resistant

0

1 (9.0)

0.28

  Any resistance

2 (7.4)

5 (45.4)

0.01

Staphylococcus aureus

N = 10

N = 22

 

  Methicillin-resistant

0

6 (27.2)

0.14

  All isolates

N = 1592

N = 2032

 

  Any resistance

32 (20.1)

71 (34.9)

0.001

  Multi-drug resistance

10 (6.2)

22 (10.8)

0.18

  1. CA strict community-acquired episodes, HCA healthcare-associated episodes.
  2. 1 all of them were ESBL producers. 2 10 and 11 episodes, respectively, were polymicrobials.