Covariables | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
OR | 95% CI | P value | OR | 95% CI | P value | |
Age (for each year of increase) | 1.00 | (1.00 – 1.01) | <0.001 | 1.00 | (1.00 – 1.00) | 0.445 |
Sex | ||||||
Female | 1 | Reference | 1 | Reference | ||
Male | 1.07 | (1.00 – 1.15) | 0.037 | 0.97 | (0.92 – 1.02) | 0.236 |
Site | ||||||
Community | 1 | Reference | 1 | Reference | ||
Hospital | 1.12 | (1.04 – 1.20) | 0.002 | 1.03 | (0.96 – 1.09) | 0.409 |
Source of infection | ||||||
Urinary | 1 | Reference | 1 | Reference | ||
Respiratory | 1.53 | (1.38 – 1.68) | <0.001 | 1.21 | (1.11 – 1.33) | <0.001 |
Skin and soft tissues | 0.81 | (0.73 – 0.91) | <0.001 | 0.91 | (0.84 – 1.00) | 0.041 |
Intra-abdominal | 1.64 | (1.46 – 1.84) | <0.001 | 1.32 | (1.20 – 1.46) | <0.001 |
Other infections | 1.33 | (1.22 – 1.44) | <0.001 | 1.16 | (1.08 – 1.25) | <0.001 |
Comorbidities | ||||||
Without comorbidities | 1 | Reference | 1 | Reference | ||
With any comorbidity | 1.30 | (1.21 – 1.40) | <0.001 | 1.01 | (0.95 – 1.07) | 0.774 |
SOFA score (0 – 24, for each unit of increase) | 1.21 | (1.20 – 1.22) | <0.001 | 1.16 | (1.14 – 1.17) | <0.001 |
APACHE II score (0 – 67, for each unit of increase) | 1.08 | (1.07 – 1.08) | <0.001 | 1.02 | (1.02 – 1.03) | <0.001 |
Blood cultures | ||||||
Not requested | 1 | Reference | 1 | Reference | ||
Negative | 1.17 | (1.09 – 1.27) | <0.001 | 0.96 | (0.91 – 1.03) | 0.281 |
Gram-positive bacteria | 1.46 | (1.28 – 1.66) | <0.001 | 0.99 | (0.88 – 1.11) | 0.867 |
Gram-negative bacteria | 1.58 | (1.41 – 1.75) | <0.001 | 1.01 | (0.93 – 1.11) | 0.748 |