Table 4 Univariate analysis of risk factors in relation to the prospective genotype based clustering analysis of 129 M. tuberculosis isolates following spoligotyping and 5-loci VNTRs (clustered, n = 71 vs. unclustered, n = 58)
Risk factors | No. of patients (%) | Odds ratio (95% CI) | pvalue | |
|---|---|---|---|---|
Clustered | Unclustered | |||
Male sex | 40 (56.3) | 37 (63.8) | 0.73 [0.34-1.58] | 0.40 |
Low incomes (< 465 €) | 21 (29.6) | 14 (24.1) | 2.03 [0.73-5.68] | 0.13 |
Alcohol abuse a | 15 (21.1) | 12 (20.7) | 0.73 [0.25-2.15] | 0.50 |
Pulmonary localization of TB | 64 (90.1) | 50 (86.2) | 1.46 [0.44-4.87] | 0.50 |
Age < 60 years | 61 (85.9) | 42 (72.4) | 2.32 [0.89-6.16] | 0.06 |
HIV positive | 16 (22.5) | 9 (15.5) | 1.41 [0.51-3.96] | 0.50 |
Foreign born | 36 (50.7) | 30 (51.7) | 0.96 [0.48-1.92] | 0.90 |
Underlying conditions b | 30 (42.3) | 28 (48.3) | 0.78 [0.37-1.67] | 0.50 |
Previous medical problems c | 16 (22.5) | 19 (32.8) | 0.78 [0.25-2.41] | 0.60 |
Diagnosis delay d > 26.5 j | 44 (62.0) | 43 (74.1) | 0.57 [0.25-1.29] | 0.14 |
Hospitalization | 18 (25.4) | 10 (17.2) | 1.80 [0.64-5.13] | 0.20 |