Skip to main content

Table 1 Characteristics of patients with MRSA and non-MRSA pneumonia a

From: Prediction of methicillin-resistant Staphylococcus aureusin patients with non-nosocomial pneumonia

Characteristics

MRSA

Non-MRSA

P-value

(n=78)

(n=865)

Age

71.4 ± 9.3

66.0 ± 14.8

< 0.001

Male

58 (74.4)

565 (65.3)

0.106

Female

20 (25.6)

300 (34.7)

Type of pneumonia

   

   Community acquired

21 (26.9)

475 (54.9)

< 0.001

   Health care associated

57 (73.1)

390 (45.1)

Underlying diseases

   

   Diabetes mellitus

30 (38.5)

237 (27.4)

0.038

   Chronic lung diseaseb

20 (25.6)

239 (27.6)

0.706

   Cerebral vascular accident

22 (28.2)

162 (18.7)

0.043

   Renal disease

14 (17.9)

104 (12.0)

0.13

   Hypertension

44 (9.7)

408 (47.2)

0.118

   Cardiovascular disease

21 (26.9)

148 (17.1)

0.03

   Liver disease

6 (7.7)

50 (5.8)

0.454

   Rheumatologic disease

3 (3.8)

31 (3.6)

0.756

   Malignancy

36 (46.2)

303 (35.0)

0.05

Clinical manifestation and parameters

   

   Bloody sputum

1 (1.3)

42 (4.9)

0.147

   Confusion (decreased consciousness)

17 (21.8)

134 (15.5)

0.146

   Shock at onset

20 (25.6)

267 (30.9)

0.337

   Hypoxemiac

49 (62.8)

437 (50.5)

0.037

   Acute renal failure at onset

13 (16.7)

162 (18.7)

0.654

   Leukocytes /uL

12700 ± 7700

11800 ± 7300

0.341

   Blood urea nitrogen > 30 mg/dL

25 (32.1)

255 (29.5)

0.634

   Sodium < 130 mmol/L

15 (19.2)

132 (15.3)

0.355

   pH < 7.35

7 (9)

72 (8.3)

0.843

Immunosuppressedd

24 (30.8)

215 (24.9)

0.25

MRSA history in previous 1 year

20 (25.6)

33 (3.8)

< 0.001

Tube feeding

12 (15.4)

64 (7.4)

0.013

CURB65

1.94 ± 1.07

1.6 ± 1.15

0.015

Pneumonia Severity Index

144.7 ± 26.1

127.6 ± 38.4

< 0.001

Admission via ER

64 (82.1)

700 (80.9)

0.808

  1. aData are presented as numbers (percentages) and plus-minus values are means ± standard deviation unless otherwise indicated.
  2. bChronic lung disease includes asthma, COPD, and structural lung diseases, such as bronchiectasis and interstitial lung disease.
  3. cPaO2 < 60 mmHg, SpO2 < 90% or need for oxygen therapy.
  4. dImmunosuppression includes the following: (1) daily administration of systemic corticosteroids (at least 15 mg of prednisone per day for more than one month or combination therapy with low dose corticosteroids and other immunosuppressants including azathioprine, mycophenolate, methotrexate, cyclosporine, or cyclophosphamide); (2) seropositivity for human immunodeficiency virus; (3) received either a solid organ transplant or bone marrow transplant; (4) treated with radiation therapy or chemotherapy for an underlying malignancy during the 6 months prior to hospital admission; (5) an underlying acquired immune deficiency disorder.
  5. Abbreviations: MRSA methicillin-resistant Staphylococcus aureus, ER emergency room.