Antimicrobial susceptibility and genetic characteristics of Neisseria gonorrhoeae isolates from Vietnam, 2011

BMC Infectious Diseases

Table 2 Neisseria gonorrhoeae with decreased susceptibility or resistance to cefixime or ceftriaxone (≥0.125) isolated in Hanoi, Vietnam in 2011 (n = 30)

NG-MAST	Minimum inhibitory concentration		penAalteration	mtrRalteration		PorB1b (penBalteration)
	Cefixime	Ceftriaxone	A501 alteration (penAallele [[16]])	A-deletion in promoter region	MtrR coding region	G101	A102
ST4787 (n = 1)	0.25	0.25	T (XVIII)	Yes	A39T	K	D
ST4787 (n = 2)	0.125	0.25	T (XVIII)	Yes	A39T	K	D
ST4787 (n = 1)	0.125	0.125	V (A501 New**)	Yes	H105Y	K	D
ST4787 (n = 3)	0.064	0.125	T (XVIII)	Yes	A39T	K	D
ST4787 (n = 1)	0.032	0.125	T (XVIII)	Yes	A39T	K	D
ST7159 (n = 2)	0.064	0.125/0.25	T (XVIII)	Yes	D79N T86A H105Y	K	D
ST4676 (n = 1)	0.125	0.25	T (XVIII)	Yes	H105Y	K	G
3 STs^a (n = 4)	0.125	0.125	T (XVIII)	Yes	A39T	K/D^b	D/G^b
12 STs (n = 15)	0.064	0.125	T/V/WT^c	Yes	A39T G45D H105Y^d	K/D/T^e	D/G/WT^e

NG-MAST, Neisseria gonorrhoeae multiantigen sequence typing; ST, sequence type.
^a ST7739 (n = 2), ST7160 (n = 1) and ST7741 (n = 1).
^b G101D/A102G (n = 2) and G101K/A102D (n = 1).
^c A501V New** (n = 9), XVIII (n = 3), XIII (n = 2) and XII (n = 1).
^d H105Y (n = 8), A39T (n = 4), and G45D (n = 3).
^e G101K/A102D (n = 11), G101D/A102G (n = 2), G101D/WT (n = 1), G101T/A102D (n = 1).

ISSN: 1471-2334