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Table 2 Univariate analysis of factors associated with time to positivity in C. albicans BSIs

From: Time to blood culture positivity as a predictor of clinical outcome in patients with Candida albicansbloodstream infection

Variables   Time to positivity ≤36 hs (n=39)   Time to positivity >36 hs (n=50) P
N % N %  
Demographic characteristics      
Age, mean years ±SD 58.4±17.8   65.6±14.8   0.04
Male 25 64.1 29 58.0 0.56
Underlying conditions      
Charlson ≥ 3 23 59.0 26 52.0 0.51
Rapidly fatal disease (MacCabe) 26 66.7 28 56.0 0.31
Diabetes 6 15.4 13 26.0 0.23
Neoplasia 16 41.0 10 20.0 0.03
Neutropenia 1 2.6 2 4.0 0.44
Surgery 24 61.5 26 52.0 0.34
Blood transfusion 21 53.8 15 30.0 0.02
Conditions related to the clinical course      
APACHE II score ≥ 20 at BSI onset 11 28.2 23 46.0 0.09
Adequate antifungal therapy 13 33.3 7 14.0 0.03
Source of infection      
Intravascular catheter 22 56.4 16 32.0 0.04
Gastrointestinal 7 17.9 23 46.0 0.01
Respiratory tract 5 12.8 4 8.0 0.45
Urinary tract 3 7.7 5 10.0 0.71
Other 2 5.2 2 4.0 0.83
Outcomes      
Organ failure 31 79.5 38 76.0 0.70
Septic shock 18 46.2 20 40.0 0.56
Respiratory failure 26 66.7 36 72.0 0.59
Renal failure 15 38.5 18 36.0 0.81
Hematologic failure 1 2.6 4 8.0 0.26
Hepatic failure 3 7.7 5 10.0 0.71
In-hospital mortality 29 74.4 41 82.0 0.38