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Table 3 Risk factors for hospital mortality in patients with C. albicans BSI

From: Time to blood culture positivity as a predictor of clinical outcome in patients with Candida albicansbloodstream infection

Variables  Died (n=70)  Recovered (n=19)  Univariate analysis  Multivariate analysis
N % N % OR CI 95% OR CI 95%
Age >60 years 43 61.4 8 42.0 2.2 0.78-6.13   
Male gender 45 64.3 9 47.4 0.5 0.18-1.39   
APACHE II score20 at BSI onset 32 45.7 2 10.5 7.2 1.54-33.35 2.1 0.3-12.8
Organ failure (at least one) 59 84.2 10 52.5 4.8 1.60-14.60 2.9 0.6-13.2
Respiratory failure 54 77.1 8 42.1 4.6 1.60-13.50   
Cardiovascular failure 35 50.0 3 15.8 5.3 1.43-19.95   
Renal failure 29 41.4 4 21.0 2.7 0.80-8.82   
Hematologic failure 5 7.1 - - 1.3 1.15-1.45   
Hepatic failure 8 11.4 - - 1.3 1.16-1.47   
Inadequate antifungal therapy 55 78.6 14 73.7 1.31 0.41-4.22   
Charlson score ≥3 40 57.1 9 47.3 1.5 0.54-4.10   
Neoplasia 20 28.5 6 31.5 0.9 0.29-2.60   
SOFA at BSI onset, mean (±SD) 6.7 (4.3) 3.6 (2.3) 1.28 1.07-1.52 1.05 0.8-1.3
SAPS II at BSI onset, mean (±SD) 48.4 (15.4) 35.2 (14.3) 1.06 1.02-1.11 1.04 0.9-1.1
Time to positivity (in hours), mean (±SD) 43.9 (19.8) 34.6 (15.4) 1.03 1.0-1.06 1.04 1.0-1.1