Variables | Died (n=70) | Recovered (n=19) | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|---|---|
N | % | N | % | OR | CI 95% | OR | CI 95% | |
Age >60 years | 43 | 61.4 | 8 | 42.0 | 2.2 | 0.78-6.13 | ||
Male gender | 45 | 64.3 | 9 | 47.4 | 0.5 | 0.18-1.39 | ||
APACHE II score ≥20 at BSI onset | 32 | 45.7 | 2 | 10.5 | 7.2 | 1.54-33.35 | 2.1 | 0.3-12.8 |
Organ failure (at least one) | 59 | 84.2 | 10 | 52.5 | 4.8 | 1.60-14.60 | 2.9 | 0.6-13.2 |
Respiratory failure | 54 | 77.1 | 8 | 42.1 | 4.6 | 1.60-13.50 | ||
Cardiovascular failure | 35 | 50.0 | 3 | 15.8 | 5.3 | 1.43-19.95 | ||
Renal failure | 29 | 41.4 | 4 | 21.0 | 2.7 | 0.80-8.82 | ||
Hematologic failure | 5 | 7.1 | - | - | 1.3 | 1.15-1.45 | ||
Hepatic failure | 8 | 11.4 | - | - | 1.3 | 1.16-1.47 | ||
Inadequate antifungal therapy | 55 | 78.6 | 14 | 73.7 | 1.31 | 0.41-4.22 | ||
Charlson score ≥3 | 40 | 57.1 | 9 | 47.3 | 1.5 | 0.54-4.10 | ||
Neoplasia | 20 | 28.5 | 6 | 31.5 | 0.9 | 0.29-2.60 | ||
SOFA at BSI onset, mean (±SD) | 6.7 (4.3) | 3.6 (2.3) | 1.28 | 1.07-1.52 | 1.05 | 0.8-1.3 | ||
SAPS II at BSI onset, mean (±SD) | 48.4 (15.4) | 35.2 (14.3) | 1.06 | 1.02-1.11 | 1.04 | 0.9-1.1 | ||
Time to positivity (in hours), mean (±SD) | 43.9 (19.8) | 34.6 (15.4) | 1.03 | 1.0-1.06 | 1.04 | 1.0-1.1 |