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Table 3 Risk factors for hospital mortality in patients with C. albicans BSI

From: Time to blood culture positivity as a predictor of clinical outcome in patients with Candida albicansbloodstream infection

Variables

 Died (n=70)

 Recovered (n=19)

 Univariate analysis

 Multivariate analysis

N

%

N

%

OR

CI 95%

OR

CI 95%

Age >60 years

43

61.4

8

42.0

2.2

0.78-6.13

  

Male gender

45

64.3

9

47.4

0.5

0.18-1.39

  

APACHE II score20 at BSI onset

32

45.7

2

10.5

7.2

1.54-33.35

2.1

0.3-12.8

Organ failure (at least one)

59

84.2

10

52.5

4.8

1.60-14.60

2.9

0.6-13.2

Respiratory failure

54

77.1

8

42.1

4.6

1.60-13.50

  

Cardiovascular failure

35

50.0

3

15.8

5.3

1.43-19.95

  

Renal failure

29

41.4

4

21.0

2.7

0.80-8.82

  

Hematologic failure

5

7.1

-

-

1.3

1.15-1.45

  

Hepatic failure

8

11.4

-

-

1.3

1.16-1.47

  

Inadequate antifungal therapy

55

78.6

14

73.7

1.31

0.41-4.22

  

Charlson score ≥3

40

57.1

9

47.3

1.5

0.54-4.10

  

Neoplasia

20

28.5

6

31.5

0.9

0.29-2.60

  

SOFA at BSI onset, mean (±SD)

6.7 (4.3)

3.6 (2.3)

1.28

1.07-1.52

1.05

0.8-1.3

SAPS II at BSI onset, mean (±SD)

48.4 (15.4)

35.2 (14.3)

1.06

1.02-1.11

1.04

0.9-1.1

Time to positivity (in hours), mean (±SD)

43.9 (19.8)

34.6 (15.4)

1.03

1.0-1.06

1.04

1.0-1.1