Characteristics | Total N = 294 | Colistin N = 119 | Tigecycline N = 175 | p- value |
---|---|---|---|---|
Age | 63.8 (18.5) | 63.7 (19.5) | 63.8 (17.9) | .95 |
Male | 198 (67.3) | 86 (72.3) | 112 (64) | .16 |
APACHE II score | 22.5 (9.1) | 22.8 (9.3) | 22.3 (8.9) | .68 |
Length of hospital stay before enrollment | 32.0 (36.9) | 33.2 (45.9) | 31.2 (29.4) | .64 |
Underlying diseases | Â | Â | Â | Â |
 Cardiovascular disease | 47 (16.0) | 17 (14.3) | 30 (17.1) | .63 |
 Diabetes mellitus | 84 (28.6) | 33 (27.7) | 51 (29.1) | .90 |
Insulin use | 63 (21.4) | 28 (23.5) | 35 (20) | .47 |
 Chronic kidney disease | 59 (20.1) | 28 (23.5) | 31 (17.7) | .24 |
 Liver cirrhosis | 13 (4.4) | 4 (3.4) | 9 (5.1) | .57 |
 Chronic pulmonary disease | 30 (10.2) | 15 (12.6) | 15 (8.6) | .33 |
 Malignancy | 36 (12.2) | 34 (28.6) | 2 (1.1) | <.001 |
 Autoimmune | 16 (5.4) | 5 (4.2) | 11 (6.3) | .60 |
 Operation history | 140 (47.6) | 51 (42.9) | 89 (50.9) | .19 |
Combination therapy | Â | Â | Â | Â |
 Aminoglycoside | 4 (1.4) | 1 (0.8) | 3 (1.7) | .65 |
 Carbapenem | 34 (11.6) | 15 (12.6) | 19 (10.9) | .65 |
 Sulbactam | 10 (3.4) | 2 (1.7) | 8 (4.6) | .21 |
Baseline creatinine (mg/dL) | 1.75 (1.47) | 1.66 (1.43) | 1.81 (1.50) | .40 |
Duration of treatment | 13.7 (12.5) | 14.6 (13.7) | 13.1 (11.6) | .31 |
Follow-up duration | 32.4 (31.5) | 33.1 (30.9) | 31.9 (32.0) | .75 |