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Table 1 Clinical and paraclinical features during hospitalisation and follow-up of a patient with African trypanosomiasis

From: Outcome of acute East African trypanosomiasis in a Polish traveller treated with pentamidine

 

D0

D3

D7

D15

D30

D60

D90

D 120

 

28-7

31-7

3-8

13-8

2-9

30-9

28-10

8-12

Inoculation chancre

+

+

+

+

+/−

-

-

-

Fever

+

+

-

-

-

-

-

-

Anaemia

-

+

+

+

+

-

-

-

Jaundice

+

+

+

-

-

-

-

-

Splenomegaly

+

+

+

-

-

-

-

-

Spontaneous bleeding

+

+

-

-

-

-

-

-

Respiratory distress

+

+

-

-

-

-

-

-

Renal injury

+

+

-

-

-

-

-

-

Hgb (g/dl)

14.5

13.8

10.0

9.2

10.6

15.1

16.4

16.2

Thrombocytes (n/ÎŒl)

10000

9000

70000

445000

370000

216000

206000

216000

Parasitaemia (n/ÎŒl)

100000

0

0

0

0

0

0

0

ALT (IU/l)

208

362

68

18

20

30

34

29

AST (IU/l)

217

237

48

12

12

20

21

20

Bilirubin (total, mg/dl)

2.37

3.48

4.52

0.76

0.60

0.55

0.68

0.75

Fibrinogen (mg/dl)

173

125

136

256

276

281

274

278

Creatinine (mg/dl)

2.92

1.71

0.57

0.46

0.70

0.91

0.96

0.96

Tbgam IFAT

-

 

-

-

-

-

-

-

Tbgam CATT

-

 

-

-

-

-

-

-

Tbrhod ETat 1:1

-

 

+

+

+

-

-

-

Tbrhod ETat 1:18

-

 

-

-

-

-

-

-

Total serum IgM (mg/l)

1610

 

3530

7030

5050

3370

3120

2170

T.brucei complex PCR-RFLP

+

       

T.b.rhod. PCR SLG polymorphism

+

       

T.b.rhod PCR SRA

+ (287 bp)

       
  1. Abbreviations: Hgb hemoglobin, ALT alanine aminotransferase, AST aspartate aminotransferase, Tbgam Trypanosoma brucei gambiense, Tbrhod Trypanosoma brucei rhodesiense, CATT Card Agglutination Test for Trypanosomiasis, IFAT Indirect Fluorescent Antibody Test, ETat Edinburgh Trypanosoma Antigenic Type, PCR Polymerase Chain Reaction, RFLP Restriction Fragment Length Polymorphism, SLG Spliced Leader Gene Polymorphism Marker, SRA Serum Resistance-Associated Gene, “-“ negative result, “+” positive result, bp: base pair.