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Table 2 Cost-effectiveness and threshold prices under varying programmatic assumptions (2012 US$)*

From: Cost-effectiveness of tenofovir gel in urban South Africa: model projections of HIV impact and threshold product prices

  

Cost per DALY averted at $0.25 per dose

Microbicide threshold prices where $/infection averted (IA) = VMMC (~$1000/IA)

  

2 doses per sex-act

1 dose per sex-act

2 gels per sex-act

 

Baseline programme: 3 annual HIV tests, 3 gel collection visits

 

$297

   

$0.12

 

Variations to distribution services

       

HIV tests per year

2

$190

-36%

-$29

-137%

$0.19

49%

 

4

$405

36%

$186

137%

$0.06

-49%

 

6

$619

108%

$401

411%

Cannot be achieved

 

Adherence counselling and gel collection visits

2

$272

-9%

$53

-32%

$0.14

12%

 

6

$374

26%

$155

97%

$0.08

-35%

Integrated adherence counselling and gel collection into HIV testing (3)

 

$221

-26%

$2

-97%

$0.17

35%

  1. *Assuming 30% uptake after 10 years and trial consistency of gel use and mean imputed efficacy estimates, 10% product wastage during distribution, and a 3% discount rate on costs and effects.