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Table 4 ERV3 and respiratory virus positive samples detected by polymerase chain reaction assays in 3366 parent collected nasal swab specimens

From: Nasal swab samples and real-time polymerase chain reaction assays in community-based, longitudinal studies of respiratory viruses: the importance of sample integrity and quality control

Variable

No. samples (%)

ERV3 Positive

Respiratory virus positive

  

No. samples (%)

Univariate

*Multivariate

No. samples (%)

Univariate

*Multivariate

    

OR (95% CI); P value

OR (95%); P value

 

OR (95% CI); P value

OR (95%); P value

Age (months)

< 6

1293 (38.4%)

995 (77.0)

1

1

208 (16.1)

1

1

6- <12

1295 (38.5%)

1061 (81.9)

1.20 (0.94-1.53); 0.15

1.28 (0.98-1.68); 0.07

411 (31.7)

2.59 (2.07-3.24); <0.001

2.38 (1.89-3.01); <0.001

≥12

778 (23.1%)

662 (85.1)

1.49 (1.06-2.10); 0.02

1.93 (1.27-2.93); 0.002

266 (34.2)

2.98 (2.26-3.92); <0.001

2.16 (1.57-2.99); <0.001

Gender

Male

1647 (48.9%)

1335 (81.1)

1

1

461 (28.1)

1

1

Female

1719 (51.06%)

1383 (80.4)

0.81 (0.54-1.22); 0.32

0.87 (0.58-1.29); 0.48

424 (24.7)

0.82 (0.60-1.12); 0.21

0.83 (0.61-1.12); 0.23

Collector

Mother

2845 (84.5%)

2307 (81.1)

1

1

766 (26.9)

1

1

Father

441 (13.1%)

342 (77.6)

0.91 (0.66-1.27); 0.60

0.87 (0.62-1.22); 0.42

109 (24.7)

0.94 (0.70-1.26); 0.67

0.88 (0.65-1.19); 0.41

Research staff

45 (1.3%)

40 (88.9)

2.71 (1.00-7.36); 0.05

1.76 (0.65-4.81); 0.27

3 (6.7)

0.24 (0.07-0.79); 0.02

0.36 (0.11-1.21); 0.10

Other

35 (1.0%)

29 (82.9)

1.31 (0.49-3.51); 0.59

1.39 (0.46-4.16); 0.56

7 (20.0)

0.72 (0.30-1.74); 0.47

0.87 (0.35-2.13); 0.76

Season

Summer

926 (27.5%)

729 (78.7)

1

1

178 (19.2)

1

1

Autumn

1059 (31.5%)

802 (75.7)

0.90 (0.71-1.13); 0.37

0.74 (0.58-0.96); 0.02

304 (28.7)

1.99 (1.59-2.49); <0.001

1.74 (1.38-2.20); <0.001

Winter

541 (16.1%)

482 (89.1)

2.63 (1.87-3.70); <0.001

2.41 (1.67-3.49); <0.001

198 (36.6)

3.06 (2.36-3.97); <0.001

2.63 (2.01-3.45); <0.001

Spring

840 (25.0%)

705 (83.9)

1.39 (1.07-1.79); 0.01

1.50 (1.13-1.99); 0.005

205 (24.4)

1.27 (1.00-1.61); 0.05

1.43 (1.11-1.84); 0.005

Mould

None

2604 (77.4%)

2189 (84.1)

1

1

707 (27.2)

1

1

Low

411 (12.2%)

308 (74.9)

0.47 (0.36-0.62); <0.001

0.69 (0.52-0.93); 0.01

97 (23.6)

0.73 (0.56-0.95); 0.02

0.81 (0.61-1.07); 0.14

Medium

252 (7.5%)

163 (64.7)

0.27 (0.20-0.37); <0.001

0.47 (0.33-0.66); <0.001

60 (23.8)

0.70 (0.50-0.96); 0.03

0.70 (0.49-0.99); 0.05

High

99 (2.9%)

58 (58.6)

0.20 (0.13-0.33); <0.001

0.40 (0.24-0.66); <0.001

21 (21.2)

0.57 (0.34-0.96); 0.04

0.53 (0.31-0.93); 0.03

Time to reach Laboratory (days)

0 - 3

2281 (67.8%)

1983 (86.9)

1

1

587 (25.7)

1

1

4 - 7

723 (21.5%)

513 (71.0)

0.32 (0.25-0.40); <0.001

0.39 (0.30-0.50); <0.001

187 (25.9)

0.96 (0.78-1.18); 0.69

1.03 (0.82-1.29);0.80

 

> 7

362 (10.8%)

222 (61.3)

0.17 (0.13-0.24); <0.001

0.24 (0.17-0.34); <0.001

111 (30.7)

1.16 (0.89-1.52); 0.28

1.42 (1.05-1.94); 0.02

  1. *Adjusted for all variables in the Table.