Table 1 Characteristics of the 39 patients with rifampicin monoresistant tuberculosis reported in France between 2005 and 2010
From: Rifampicin mono-resistant tuberculosis in France: a 2005–2010 retrospective cohort analysis
Characteristic | Total | History of treatment | P value | |
|---|---|---|---|---|
N(%) | No N(%) | Yes N(%) | ||
Total patients | 39 (100) | 20 (100) | 19 (100) | |
Male | 19 (49) | 8 (45) | 11 (58) | 0.63 |
Age median [IQR] | 43 [29–58] | 38.5 [24.5–58] | 44 [36–58] | |
≥ 40 years old | 21 (54) | 10 (50) | 11 (58) | 0.62 |
Foreign born patients | 18 (46) | 12 (60) | 6 (31) | 0.07 |
If yes, year of arrival in France: | ||||
< 5 years | 10 | 8 | 2 | |
5–10 years | 4 | 2 | 2 | |
≥ 19 years | 3 | 1 | 2 | |
NA | 1 | 1 | ||
Travel ≤ 2 years before diagnosis: | ||||
Yes | 10 (26) | 7 (35) | 3 (16) | 0.38 |
No | 25 (64) | 11 (55) | 14 (74) | |
NA | 4 | 2 | 2 | |
Social disadvantage | 9 (23) | 3 (15) | 6 (30) | 0.12 |
Collectivity | 5 (13) | 3 (15) | 2 (10) | 0.31 |
History of tuberculosis before diagnosis: | 20 (51) | 1* (5) | 19 (100) | |
< 5 years | 15 | 15 | ||
> 20 years | 3 | 1* | 2 | |
NA | 2 | 2 | ||
History of: | ||||
-Incarceration | 0 | 0 | 0 | - |
-Intravenous drug user | 3 (8) | 1 (5) | 2 (10.5) | 0.40 |
-Tuberculosis exposure | 5 (13) | 4 (20) | 1 (5) | 0.38 |
-Alcohol use | 9 (23) | 2 (10) | 7 (37) | 0.04 |
-Immunosuppression | 4 (10) | 3 (15) | 1 (5) | 0.32 |
HIV co-infection | 9 (23) | 2 (10) | 7 (37) | 0.04 |
Site of tuberculosis: | ||||
-Pulmonary | 24 (61.5) | 12 (60) | 12 (63) | 0.94 |
-Extra-pulmonary | 8 (20.5) | 4 (20) | 4 (21) | |
-Pulmonary and extra-pulmonary | 7 (18) | 4 (20) | 3 (16) | |
Smear-positive | 24 (62%) | 7 (35%) | 17 (89%) | <0.001 |