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Table 2 Laboratory data of patients who did and did not recover from acute kidney injury (AKI)

From: Acute kidney injury due to anti-tuberculosis drugs: a five-year experience in an aging population

 

No. of patients with data

Overall (n = 99)

AKI-recovered (n = 71)

AKI-unrecovered (n = 26)

Loss of follow-up (n = 2)

Baseline

 Creatinine (μmol/L)

99

88.4 [55.2-132.6]

88.4 [70.7-132.6]

88.4 [61. 9–150.3]

62 [53–71]

 Uric Acid (μmol/L)

82

374.7 [285.5-440.2]

374.7 [267.7-434.2]

377.7 [339.0-493.7]

485 [232–738]

Onset of AKI

 Creatinine (μmol/L)

99

123.8 [97.2-246.8]

123.8 [97.2-159.1]

132.6 [106.1-238.7]

122 [84–159]

 Blood urea nitrogen (mmol/L)

76

8.4 [6.0-15.4]

7.5 [5.6-13.3]

14.5 [7.9-20.7]*

NA

 Uric Acid (mmol/L)

83

529.4 [386.6-678.1]

535.32 [386.6-695.9]

499.6 [350.9-565.1]

518 [440–595]

 Hemoglobin < 100 (g/L)

84

22 (26)

15 (25)

7 (33)

0 (0)

 Eosinophil >0.5 (109/L)

73

21 (29)

14 (25)

7 (44)

0 (0)

 White blood cell >10 (109/L)

85

15 (18)

11 (18)

4 (19)

0 (0)

 Platelet < 100 (109/L)

85

9 (11)

9 (15)

0 (0)**

0 (0)

 Hepatitis#

97

4 (4)

3 (4)

1 (4)

0 (0)

 Jaundice§

81

3 (4)

2 (3)

1 (6)

0 (0)

 Hypoalbuminemia

94

39 (41)

24 (36)

14 (54)

1 (50)

 Hematuria

35

5 (5)

2 (7)

3 (38)*

0 (0)

 Proteinuria

35

20 (20)

13 (48)

7 (88)*

0 (0)

 Sterile leukocyturia

35

17 (17)

13 (48)

4 (50)

0 (0)

  1. Note: Data are either median [inter-quartile range] or number (%) unless otherwise stated.
  2. *Significantly different (p < 0.05) between the AKI-recovered and –unrecovered groups.
  3. **p = 0.064.
  4. #Hepatitis was defined as increased serum alanine aminotransferase >3 times the upper limit of normal (ULN) in symptomatic, or >5 times the ULN in asymptomatic patients.
  5. §Jaundice was defined as serum total bilirubin level >51.3 μmol/L.