From: Acute kidney injury due to anti-tuberculosis drugs: a five-year experience in an aging population
No. of patients with data | Overall (n = 99) | AKI-recovered (n = 71) | AKI-unrecovered (n = 26) | Loss of follow-up (n = 2) | |
---|---|---|---|---|---|
Baseline | |||||
Creatinine (μmol/L) | 99 | 88.4 [55.2-132.6] | 88.4 [70.7-132.6] | 88.4 [61. 9–150.3] | 62 [53–71] |
Uric Acid (μmol/L) | 82 | 374.7 [285.5-440.2] | 374.7 [267.7-434.2] | 377.7 [339.0-493.7] | 485 [232–738] |
Onset of AKI | |||||
Creatinine (μmol/L) | 99 | 123.8 [97.2-246.8] | 123.8 [97.2-159.1] | 132.6 [106.1-238.7] | 122 [84–159] |
Blood urea nitrogen (mmol/L) | 76 | 8.4 [6.0-15.4] | 7.5 [5.6-13.3] | 14.5 [7.9-20.7]* | NA |
Uric Acid (mmol/L) | 83 | 529.4 [386.6-678.1] | 535.32 [386.6-695.9] | 499.6 [350.9-565.1] | 518 [440–595] |
Hemoglobin < 100 (g/L) | 84 | 22 (26) | 15 (25) | 7 (33) | 0 (0) |
Eosinophil >0.5 (109/L) | 73 | 21 (29) | 14 (25) | 7 (44) | 0 (0) |
White blood cell >10 (109/L) | 85 | 15 (18) | 11 (18) | 4 (19) | 0 (0) |
Platelet < 100 (109/L) | 85 | 9 (11) | 9 (15) | 0 (0)** | 0 (0) |
Hepatitis# | 97 | 4 (4) | 3 (4) | 1 (4) | 0 (0) |
Jaundice§ | 81 | 3 (4) | 2 (3) | 1 (6) | 0 (0) |
Hypoalbuminemia | 94 | 39 (41) | 24 (36) | 14 (54) | 1 (50) |
Hematuria | 35 | 5 (5) | 2 (7) | 3 (38)* | 0 (0) |
Proteinuria | 35 | 20 (20) | 13 (48) | 7 (88)* | 0 (0) |
Sterile leukocyturia | 35 | 17 (17) | 13 (48) | 4 (50) | 0 (0) |