From: The epidemiology of childhood tuberculosis in the Netherlands: still room for prevention
< 5 years | 5-14 years | Total 0–14 years | >14 years | Total (all ages) | ||||||
---|---|---|---|---|---|---|---|---|---|---|
n | % of age group | n | % of age group | n | % of age group | n | % | n | % of age group | |
Total TB cases (% of total notified) | 154 | (2%) | 249 | (3%) | 403 | (5%) | 7954 | (95%) | 8357 | (100%) |
Male | 82 | 53% | 112 | 45% | 194 | 48% | 4574 | 58% | 4768 | 57% |
Dutch born, including both parents | 33 | 21% | 69 | 28% | 102 | 25% | 1914 | 24% | 2016 | 24% |
Dutch born, 2d generation immigrant | 91 | 59% | 63 | 25% | 154 | 38% | 381 | 5% | 535 | 6% |
Foreign-born | 30 | 19% | 116 | 47% | 146 | 36% | 5,645 | 71% | 5791 | 69% |
WHO incidence 2008 country of origin | ||||||||||
<50 | 4 | 13% | 8 | 7% | 12 | 8% | 870 | 15% | 882 | 16% |
50-199 | 7 | 23% | 24 | 21% | 31 | 21% | 2673 | 47% | 2704 | 48% |
>200 | 19 | 63% | 84 | 70% | 68% | 2116 | 37% | 2185 | 39% | |
Site of TB disease | ||||||||||
- Primary TB infection | 72 | 47% | 69 | 28% | 141 | 35% | 117 | 1% | 258 | 3% |
- Pulmonary TB | 51 | 33% | 86 | 35% | 137 | 34% | 4189 | 53% | 4326 | 52% |
- TB pleuritis | 1 | 1% | 7 | 3% | 8 | 2% | 560 | 7% | 568 | 7% |
- Other TB of respiratory tract, including intrathoracic lymph nodes | 15 | 10% | 35 | 14% | 50 | 12% | 896 | 11% | 946 | 11% |
- TB of peripheral lymph nodes | 7 | 5% | 32 | 13% | 39 | 10% | 1260 | 16% | 1299 | 16% |
- miliary TB | 3 | 2% | 7 | 3% | 10 | 2% | 203 | 3% | 213 | 3% |
- TB meningitis | 3 | 2% | 4 | 2% | 7 | 2% | 177 | 2% | 184 | 2% |
- Bone and joint TB | 0 | 0% | 5 | 2% | 5 | 1% | 341 | 4% | 346 | 4% |
- TB of other organ tracts | 2 | 1% | 10 | 4% | 12 | 3% | 732 | 9% | 744 | 9% |
Culture positive | 36 | 23% | 93 | 37% | 129 | 32% | 5,867 | 74% | 4611 | 55% |
History of TB contact | 105 | 68% | 132 | 53% | 237 | 59% | 606 | 8% | 843 | 10% |
Hiv-co-infection | 1 | 1% | 2 | 1% | 1% | 326 | 4% | 329 | 4% | |
Diagnosis by MPHS | 104 | 68% | 140 | 56% | 244 | 61% | 1509 | 19% | 1753 | 21% |
Active case finding | ||||||||||
- Contact investigation | 101 | 66% | 128 | 51% | 229 | 57% | 390 | 5% | 619 | 7% |
- Screening immigrants | 11 | 7% | 18 | 7% | 29 | 7% | 856 | 11% | 885 | 11% |
Hospital admission >1 week | 23 | 15% | 41 | 16% | 64 | 16% | 2652 | 33% | 2716 | 32% |
Daily observed treatment | 88 | 57% | 116 | 47% | 204 | 51% | 2114 | 27% | 2318 | 28% |
Adverse events* | 4 | 3% | 12 | 5% | 16 | 4% | 1022 | 13% | 1038 | 12% |
Treatment Outcome | 135 | 218 | 353 | 7046 | 7399 | |||||
- Success | 124 | 92% | 207 | 95% | 331 | 94% | 6070 | 86% | 6401 | 87% |
- Defaulted | 5 | 4% | 3 | 1% | 8 | 2% | 255 | 4% | 263 | 4% |
- Death caused by TB | 2 | 1% | 1 | 0% | 3 | 1% | 135 | 2% | 138 | 2% |
- Death caused by other cause | 1 | 1% | 0 | 0% | 1 | 0.3% | 271 | 4% | 272 | 4% |
- Transfer out/unknown | 3 | 2% | 7 | 3% | 10 | 3% | 315 | 4% | 325 | 4% |