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Table 1 Characteristics of TB cases in the Netherlands 2005-2012

From: The epidemiology of childhood tuberculosis in the Netherlands: still room for prevention

 

< 5 years

5-14 years

Total 0–14 years

>14 years

Total (all ages)

 

n

% of age group

n

% of age group

n

% of age group

n

%

n

% of age group

Total TB cases (% of total notified)

154

(2%)

249

(3%)

403

(5%)

7954

(95%)

8357

(100%)

Male

82

53%

112

45%

194

48%

4574

58%

4768

57%

Dutch born, including both parents

33

21%

69

28%

102

25%

1914

24%

2016

24%

Dutch born, 2d generation immigrant

91

59%

63

25%

154

38%

381

5%

535

6%

Foreign-born

30

19%

116

47%

146

36%

5,645

71%

5791

69%

WHO incidence 2008 country of origin

          

<50

4

13%

8

7%

12

8%

870

15%

882

16%

50-199

7

23%

24

21%

31

21%

2673

47%

2704

48%

>200

19

63%

84

70%

 

68%

2116

37%

2185

39%

Site of TB disease

          

- Primary TB infection

72

47%

69

28%

141

35%

117

1%

258

3%

- Pulmonary TB

51

33%

86

35%

137

34%

4189

53%

4326

52%

- TB pleuritis

1

1%

7

3%

8

2%

560

7%

568

7%

- Other TB of respiratory tract, including intrathoracic lymph nodes

15

10%

35

14%

50

12%

896

11%

946

11%

- TB of peripheral lymph nodes

7

5%

32

13%

39

10%

1260

16%

1299

16%

- miliary TB

3

2%

7

3%

10

2%

203

3%

213

3%

- TB meningitis

3

2%

4

2%

7

2%

177

2%

184

2%

- Bone and joint TB

0

0%

5

2%

5

1%

341

4%

346

4%

- TB of other organ tracts

2

1%

10

4%

12

3%

732

9%

744

9%

Culture positive

36

23%

93

37%

129

32%

5,867

74%

4611

55%

History of TB contact

105

68%

132

53%

237

59%

606

8%

843

10%

Hiv-co-infection

1

1%

2

1%

 

1%

326

4%

329

4%

Diagnosis by MPHS

104

68%

140

56%

244

61%

1509

19%

1753

21%

Active case finding

          

- Contact investigation

101

66%

128

51%

229

57%

390

5%

619

7%

- Screening immigrants

11

7%

18

7%

29

7%

856

11%

885

11%

Hospital admission >1 week

23

15%

41

16%

64

16%

2652

33%

2716

32%

Daily observed treatment

88

57%

116

47%

204

51%

2114

27%

2318

28%

Adverse events*

4

3%

12

5%

16

4%

1022

13%

1038

12%

Treatment Outcome

135

 

218

 

353

 

7046

 

7399

 

- Success

124

92%

207

95%

331

94%

6070

86%

6401

87%

- Defaulted

5

4%

3

1%

8

2%

255

4%

263

4%

- Death caused by TB

2

1%

1

0%

3

1%

135

2%

138

2%

- Death caused by other cause

1

1%

0

0%

1

0.3%

271

4%

272

4%

- Transfer out/unknown

3

2%

7

3%

10

3%

315

4%

325

4%

  1. Definition of abbreviations: NL Netherlands, CI contact investigation, MPHS Municipal Public Health Service, HIV human immunodeficiency virus, TB tuberculosis, BCG Bacillus Calmette-Guérin.
  2. *Adverse events- defined as events demanding an interruption or change of the treatment regimen.