Characteristic | KPC(+) (n = 15) | KPC(−) (n = 60) | p-value |
---|---|---|---|
Age (mean, SD) | 59.5 (11.3) | 59.6 (17) | 0.98 |
Gender, female | 32 (53.3) | 8 (53.3) | 0.99 |
Modified APACHE II score (mean, SD) | 12.1 (5.4) | 10.8 (4.2) | 0.31 |
Prior hospitalization | 12 (80) | 28 (46.7) | 0.02 |
Neutropenic | 1 (6.7) | 1 (1.7) | 0.36 |
Renal dysfunction | 3 (20) | 10 (16.7) | 0.72 |
Liver dysfunction | 2 (13.3) | 5 (8.3) | 0.62 |
Diabetes | 3 (20) | 10 (16.7) | 0.72 |
Current immunosuppressive therapy | 1 (6.7) | 11 (18.3) | 0.44 |
LOS prior to positive culture (median, IQR) | 2 (1–12) | 1 (1–1) | <0.01 |
Time to directed therapy (hrs) (median, IQR) | 4 (0–24) | 6 (3–13) | 0.46 |
K. pneumoniae cultured from >1 site | 11 (73.3) | 19 (31.7) | <0.01 |
Total days of antibiotics post infection (median, IQR) | 13 (8–18) | 6.5 (4–10) | <0.01 |