Figure 1

Histopathologic examination of the appendix. A: Hematoxylin and eosin stain showing lymphoplasmacytic hyperplasia and scattered enlarged cells (arrow) with features characteristic of CMV-induced cytopathic changes. B: CMV immunostaining demonstrating CMV-infected cells throughout the full thickness of the bowel wall (arrows). Figure inset illustrates an infected cell at higher power view depicting cellular and nuclear enlargement with nuclear inclusions.