Table 3 Biomarkers levels measured at time of presentation in dengue fever and leptospirosis

Angiopoietin-1

44.9 (32.9-53.6)

32.3 (24.1-45.0)

35.8 (29.0-46.7)

0.236

Angiopoietin-2

1.4 (1.0-2.6)

1.8 (1.3-2.5)

2.0 (1.3-3.0)

0.474

sTie-1

8.3 (6.8-12.7)

10.1 (8.1-13.5)

9.0 (7.6-11.6)

0.120

VEGF

0.21 (0.15-0.28)

0.13 (0.05-0.30)

0.24 (0.08-0.49)

0.017

sFlt-1

0.04 (0.04-0.34)

0.04 (0.04-0.88)

0.15 (0.04-0.70)

0.864

C5a

18.5 (13.8-22.1)

53.8 (34.3-63.8)

41.2 (30.2-59.6)

0.103

CRP ^a

1.8 (1.2-6.1)

19.7 (9.1-41.4)

13.3 (4.1-39.8)

0.125

IL-10

0.02 (0.02-0.16)

0.09 (0.02-0.37)

0.08 (0.02-0.20)

0.688

CHI3L1

44.5 (35.8-61.3)

58.1 (43.0-78.6)

52.1 (36.5-74.1)

0.114

Angiopoietin-like 4

44.7 (30.2-90.9)

40.4 (30.6-57.1)

49.8 (35.9-67.8)

0.094

Angiopoietin-like 3

108 (83–118)

165 (141–195)

122 (96–148)

<0.001*

IL-18BP

5.8 (4.4-8.3)

67.8 (41.5-90.9)

11.4 (7.4 (21.5)

<0.001*

CXCL10

0.2 (0.2-0.4)

3.2 (1.2-4.4)

0.5 (0.2-1.4)

<0.001*

Platelet Factor 4 ^a

18.5 (15.6-27.1)

25.2 (16.2-39.1)

19.1 (14.0-24.6)

<0.001*

sICAM-1

169 (136–187)

352 (300–488)

228 (159–275)

<0.001*

Factor D

1143 (1018–1265)

1376 (1172–1615)

970 (837–1128)

<0.001*

sEng

6.6 (5.7-8.4)

11.7 (9.6-13.9)

7.6 (7.2-8.2)

<0.001*

sKDR

5.3 (4.5-6.1)

6.1 (5.5-7.1)

5.2 (4.6-6.1)

<0.001*

sTie-2

8.7 (6.4-9.7)

7.7 (5.9-9.3)

10.0 (7.8-13.0)

<0.001*